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Ácidos graxos ômega-3 e a resposta imune

Ácidos graxos ômega-3 e a resposta imune

          
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About the Book

O papel dos ácidos graxos poli-insaturados ômega-3 sobre o sistema imune vem sendo pesquisado nos últimos anos com o intuito de elucidar a dinâmica dos eicosanoides, derivados do ácido araquidônico, na modulação das respostas inflamatórias e na imunidade, principalmente, sobre a função dos macrófagos. A Paracoccidioidomicose é uma micose sistêmica causada pelo Paracoccidioides brasiliensis e os macrófagos são as principais células contra este patógeno. Estudos foram realizados para investigar a influência destes ácidos graxos poli-insaturados na resposta imunitária contra agentes infecciosos. Eles demonstraram que o enriquecimento de dietas com fontes dos AGPIs ômega-3 ofertadas para animais infectados com Pb diminuiu a produção da prostaglandina E2 que está envolvida na supressão da resposta imune nesta micose, em contra partida aumentou a produção dos metabólitos da fagocitose como o óxido nítrico e o peróxido de hidrogênio, além do aumento do TNF-α, principalmente no período mais tardio da infecção.


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Product Details
  • ISBN-13: 9786130172237
  • Publisher: Novas Edicoes Academicas
  • Publisher Imprint: Novas Edicoes Academicas
  • Height: 229 mm
  • No of Pages: 60
  • Series Title: Portuguese
  • Weight: 104 gr
  • ISBN-10: 6130172230
  • Publisher Date: 15 Sep 2015
  • Binding: Paperback
  • Language: Portuguese
  • Returnable: N
  • Spine Width: 4 mm
  • Width: 152 mm


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