Kayakalpa is an ancient knowledge for re-creating the human body from disability, rare disease, deformity and antimicrobial resistance (AMR). It is the oldest knowledge taught by the masers of tradition. The definition and biology of Kayakalpa are different from modern biology. There are three established biological and anatomical definitions in traditional and spiritual knowledge. As per the enumeration of the masters, the theory for the formation and development of the human body is the key understanding in terms of Kayakalpa. They are through the perspectives of worms, Gut microbes and head microbes. As per the definition of the biology of Kayakalpa the body consists of sperms and worms. The history of the sperm in the body is starting with the first sperm that is donating by the father. This is cause for conceiving a pregnancy. These sperm consist of light and vibration (vibration of sound). The sperm is activating in the mother's womb with light and vibration. This light and vibrations act to the female body to conceive as a biological property for the development of a human fetus. Within 41 minutes, this sperm will be the part of the mother's womb and this is the jacket and incubator for the fetus. After accepting this fetus to the mother's womb, it will start to multiply in an organised sequence in every micro-moment. This is happening in the Fibonacci sequence in multiplication and orientation. The orientation will be in a particular ratio and proportion is called the golden ratio. The fetus is developing from tale to head in the mother's womb. There is no active head for the fetus during this period. The first microbe is consisting of vibration, temperature, magnetic action and electric energy. Generally, we can call this is energy. Microbe generates an electric current through Electrogenesis. It can vary in every human body based on the intensity of the energy. The vibrations of energy create a heartbeat. Temperature is light. Light attracts light, dark light, attractive and repulsive forces. Magnetic action administrates attraction and repulsion. Electric energy creates relation, mind, spirit, emotion and motion. Collectively it creates the matter of the body and its attributes. In 279 days the fetus will be completed the living period inside the mother's womb. And coming out from the womb is called childbirth. Childbirth and first cry is a technical process in human life. The first cry is the important technical metabolism to activate the body. Upon the first cry, the air goes to the lungs and the breathing process is begun with it. The first cry organises hydrogen and carbon dioxide as air in the upper side of the head. The human skull is a semi-cylindrical vessel that receives the Hydrogen and carbon dioxide from the discharged air of exhalation. This stage onwards the body is producing another sperm from the head. The combination of hydrogen and carbon dioxide gases is the basic compound for producing microbe and biomass. This process is producing or forming biomass in the form of sperms within the head. In modern science, it is called the Hydrogenotrophic process. In a human body, sperms are producing from two part of the body. The first part is the Gut and the second part is from the head. This is the fundamental technology described in Kayakalpa. The Kayakalpa process helps to recreate new microbes and through that body's state to control ageing. In 14 days, an age reduction is happening up to fifty per cent.