About the Book

Exclusive, first of its kind, Indian, exhaustive, precise and yet concise textbook.
Highly illustrated guide to diseases and cancers of the blood in paediatrics.
It is a state-of-the-art book, compiled collectively, illustrated adequately, written elaborately, referenced scientifically, peer-reviewed carefully, printed in reader-friendly manner and priced economically.
Covers cancers of the blood and includes lymphoblastic leukaemia, myeloid leukaemia, juvenile myelomonocytic leukaemia, and bone marrow transplantation.
Each chapter is peer-reviewed, with a list of references.
Enhanced by nearly 200 images and illustrations.
It comes from editors who are reputed in the field with proven-track record with many successful and useful books in past.

About the Author

Editor-in-Chief: MR Lokeshwar Editors: Nitin K Shah, Bharat R Agarwal Co-editors: Mamta Vijay Manglani, Anupam Sachdeva Publication Editor: Asha Pillai

Table of Contents:
Contents Section 1 PHYSIOLOGY 1. Ontogeny of Erythropoiesis 3 Nirav Buch 2. Physiology of Blood Coagulation 10 Shrimati Shetty 3. Structure, Function and Physiology of Platelets 15 K Ghosh, Bipin P Kulkarni Section 2 NEONATAL HEMATOLOGY 4. Variation in the RBC Parameters in the Newborn 23 MR Lokeshwar, Ambreen Pandrowala, Jayashree Mondkar 5. Physiological Anemia of Newborn, Anemia of Prematurity and Role of Erythropoietin in the Management 29 Rhishikesh Thakre, PS Patil 6. Effect of Maternal Iron Status on Placenta, Fetus and Newborn 36 KN Aggarwal, Vineeta Gupta, Sonika Agarwal 7. Developmental Aspects of Hemostasis in the Fetus and Newborn 41 Bhavna Dhingra, Renu Saxena 8. Anemia in the Newborn 45 Jayashree Mondkar, Shilpa Sanjay Borse, MR Lokeshwar 9. Polycythemia and Hyperviscosity Syndrome 57 MMA Faridi, Sriram Krishnamurthy 10. Vitamin K Deficiency: Bleeding in Newborns 64 Arvind Saili, Ajay Kumar 11. Bleeding Neonate: Approach and Management 68 Mamta Vijay Manglani, Neha Vilas Dighe, Ratna Sharma, MR Lokeshwar 12. Approach to Neonatal Thrombocytopenia 77 Nitin K Shah Section 3 RBC AND WBC DISORDERS 13. Introduction and Classification of Anemias in Children 87 Manas Kalra, Satya P Yadav, Anupam Sachdeva 14. Nutritional Anemia in Infancy, Childhood and Adolescents 100 MR Lokeshwar, Nitin K Shah xxiv Textbook of Pediatric Hematology and Hemato-Oncology 15. Megaloblastic Anemia 126 Anupa A Joshipura, Nitin K Shah 16. Anemia of Chronic Disease 149 Dilraj Kaur Kahlon, Satya P Yadav, Anupam Sachdeva 17. Thalassemia Syndromes 163 Mamta Vijay Manglani, Ambreen Pandrowala, Ratna Sharma, MR Lokeshwar 18. Sickle Cell Anemia in Children 190 Swati Kanakia, Pooja Balasubramanian, MR Lokeshwar 19. Antenatal Diagnosis of Hemoglobinopathies 204 Neerja Gupta, Sadhna Arora, Madhulika Kabra 20. Red Cell Membrane Disorders (Spherocytosis, Elliptocytosis, Stomatocytosis) 213 Sunil Gomber, Pooja Dewan 21. Red Cell Enzymopathy 219 Bhavna Dhingra, Dinesh Yadav, Jagdish Chandra 22. Autoimmune Hemolytic Anemia 227 Rajiv Kumar Bansal 23. Paroxysmal Nocturnal Hemoglobinuria 238 Farah Jijina, Sonali Sadawarte 24. Diagnosis and Management of Acquired Aplastic Anemia in Children 247 Nitin K Shah 25. Inherited Bone Marrow Failure Syndromes 255 Revathi Raj 26. Benign Disorders of Neutrophils 258 Bharat R Agarwal Section 4 BLEEDING DISORDERS 27. Approach to a Bleeding Child 275 Raj Warrier, MR Lokeshwar, Aman Chauhan 28. Diagnosis and Management of Hemophilia Patients 285 Farah Jijina 29. von Willebrand Disease and Other Rare Coagulation Disorders 296 Kana Ram Jat, Ram Kumar Marwaha 30. Acquired Inhibitors of Coagulation 311 ATK Rau, Soundarya M 31. Immune Thrombocytopenic Purpura—Diagnosis and Management 318 MR Lokeshwar, Deepak K Changlani, Aparna Vijayaraghavan 32. Platelet Function Disorders 332 Shanaz Khodaiji 33. Pediatric Thrombosis 348 Rashmi Dalvi 34. Disseminated Intravascular Coagulation in Neonates 356 VP Choudhary Contents xxv Section 5 TRANSFUSION MEDICINE 35. Blood Components in Pediatric Practice 363 Nitin K Shah, Sunil Udgire 36. Nucleic Acid Amplification Testing 372 Anand Deshpande, Rajesh B Sawant 37. Transfusion Transmitted Infections 376 AP Dubey, Malobika Bhattacharya 38. Noninfectious Hazards of Blood Transfusion 384 SB Rajadhyaksha, Priti Desai Section 6 HEMATO-ONCOLOGY 39. Pediatric Acute Lymphoblastic Leukemia 395 Pankaj Dwivedi, Shripad Banavali 40. Pediatric Acute Myeloid Leukemia 408 Maya Prasad, Shripad Banavali 41. Chronic Myeloid Leukemia 419 Nirav Thacker, Brijesh Arora 42. Juvenile Myelomonocytic Leukemia 430 Gaurav Narula, Nirmalya D Pradhan 43. Pediatric Hodgkin Lymphoma 439 Amol Dongre, Brijesh Arora 44. Non-Hodgkin Lymphoma in Children and Adolescents 451 Seema Gulia, Brijesh Arora 45. Langerhans Cell Histiocytosis 462 Gaurav Narula, Nirmalya D Pradhan 46. Hemophagocytic Lymphohistiocytosis: Revisited 470 Mukesh M Desai, Sunil Udgire 47. Bone Marrow Transplantation 479 Nita Radhakrishnan, Satya P Yadav, Anupam Sachdeva Section 7 GENERAL 48. Gene Therapy 491 Aditya Kumar Gupta, Nita Radhakrishnan, Anupam Sachdeva 49. Monoclonal Antibodies in Pediatric Hematology and Oncology 496 Saroj P Panda, Girish Chinnaswamy 50. Biological Response Modifiers 501 Anupama S Borker, Narendra Chaudhary Index 511