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Statistical Human Genetics: Methods and Protocols

Statistical Human Genetics: Methods and Protocols

          
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About the Book

1. Genetic terminology

2. Identification of genotype errors

3. Detecting pedigree relationship errors

4. Identifying cryptic relationships

5. Estimating allele frequencies

6. Testing departure from Hardy-Weinberg proportions

7. Estimating disequilibrium coefficients

8. Detecting familial aggregation

9. Estimating heritability from twin studies

10. Estimating heritability from nuclear family and pedigree data

11. Correcting for ascertainment

12. Segregation analysis using the unified model

13. Design considerations for genetic linkage and association studies

14. Model-based linkage analysis of a quantitative trait

15. Model-based linkage analysis of a binary trait

16. Model-free linkage analysis of a quantitative trait

17. Model-free linkage analysis of a binary trait

18. Single marker association analysis for unrelated samples

19. Single marker family-based association analysis conditional on parental information

20. Single marker family-based association analysis not conditional on parental information

21. Allowing for population stratification in association analysis

22. Haplotype inference

23. Multi-SNP haplotype analysis methods for association analysis

24. Detecting rare variants

25. The analysis of ethnic mixtures

26. Identifying gene interaction networks

27. Structural equation modeling

28. Genotype calling for the Affymetrix platform

29. Genotype calling for the Illumina platform

30. Comparison of requirements and capabilities of major multipurpose software packages


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Product Details
  • ISBN-13: 9781493958955
  • Publisher: Humana Press
  • Publisher Imprint: Humana Press
  • Edition: Softcover reprint of the original 1st ed. 2012
  • Language: English
  • Returnable: Y
  • Spine Width: 30 mm
  • Weight: 988 gr
  • ISBN-10: 149395895X
  • Publisher Date: 23 Aug 2016
  • Binding: Paperback
  • Height: 254 mm
  • No of Pages: 564
  • Series Title: Methods in Molecular Biology
  • Sub Title: Methods and Protocols
  • Width: 178 mm


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