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Remodelage de la chromatine et transcription de l'ARN polymérase I, III

Remodelage de la chromatine et transcription de l'ARN polymérase I, III

          
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About the Book

La transcription des gènes ribosomiques par l'ARN polymérase I et l'ARN polymérase III est directement corrélée à l'état de la cellule et elle est impliquée dans la croissance cellulaire et sa réponse à la prolifération, à la différenciation, à l'état nutritionnel cellulaire et au stress. Les complexes de remodelage de la chromatine en utilisant des enzymes modifiant les histones et l'énergie de l'hydrolyse de l'ATP modifient la structure de la chromatine et l'espacement des nucléosomes pour déterminer l'accès des facteurs de transcription aux gènes à activer ou à réprimer. Le complexe de remodelage de la chromatine B-WICH composé de WSTF, SNF2h et NM1 est impliqué dans la transcription par l'ARN pol I et pol III et son association avec les gènes de l'ARNr 45S et de l'ARNr 5S, remodèle les nucléosomes au niveau du promoteur conduisant au recrutement des HAT et à l'acétylation des histones. Dans ce livre, nous essayons de montrer le rôle du complexe de remodelage de la chromatine B-WICH dans la régulation de la transcription de l'ARN pol I et III. Nous avons brièvement expliqué les gènes ribosomiques et leur structure et nous avons également présenté les principaux complexes de remodelage de la chromatine impliqués dans la transcription des gènes ribosomiques.


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Product Details
  • ISBN-13: 9786205278802
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Editions Notre Savoir
  • Height: 229 mm
  • No of Pages: 52
  • Spine Width: 3 mm
  • Width: 152 mm
  • ISBN-10: 6205278804
  • Publisher Date: 22 Oct 2022
  • Binding: Paperback
  • Language: French
  • Returnable: N
  • Weight: 91 gr


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