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Relación del cáncer de cabeza y cuello con el VPH y cambios en el p53

Relación del cáncer de cabeza y cuello con el VPH y cambios en el p53

          
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About the Book

El VPH ha demostrado ser un factor de génesis significante en el carcinoma de células escamosas de cuello uterino, pero la evidencia de la contribución del VPH en la producción del carcinoma de células escamosas de cabeza y cuello se ha estudiado por décadas y todavía permanece debatible. Los mecanismos moleculares han podido identificar la clara demostración de su capacidad de alterar los elementos del ciclo celular responsables de la división celular y la apoptosis. La literatura apoya la idea que el carcinoma de células escamosas de la orofaringe, a diferencia del carcinoma localizado en otros subsitios, posee mayor probabilidad de estar relacionado con el VPH, inclusive, se ha descrito que el carcinoma de amígdala causado por VPH del tipo 16, particularmente es considerado un tipo de tumor completamente diferente al resto de los tumores escamosos de la mucosa aéreo-digestiva superior, con comportamiento biológico, evolución y respuesta al tratamiento distintos. Este estudio lleva a considerar al VPH como un factor contribuyente en la aparición del cáncer de cabeza y cuello, sin embargo, estudios mas profundos podrán demostrar a futuro su acción directa en la génesis de este tipo de cáncer.


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Product Details
  • ISBN-13: 9783659094170
  • Publisher: Editorial Academica Espanola
  • Binding: Paperback
  • Language: Spanish
  • Returnable: N
  • Spine Width: 6 mm
  • Width: 152 mm
  • ISBN-10: 365909417X
  • Publisher Date: 12 Aug 2015
  • Height: 229 mm
  • No of Pages: 104
  • Series Title: Spanish
  • Weight: 163 gr


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Relación del cáncer de cabeza y cuello con el VPH y cambios en el p53
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Relación del cáncer de cabeza y cuello con el VPH y cambios en el p53
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