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Protein Misfolding in Neurodegenerative Diseases: Mechanisms and Therapeutic Strategies

Protein Misfolding in Neurodegenerative Diseases: Mechanisms and Therapeutic Strategies

          
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About the Book

Research focused on protein folding, misfolding, and aggregation is leading to major advances across biochemistry and medicine. The elucidation of a folding code is proving to be of extreme importance in the postgenomic era, where a number of orphan genes have been identified for which no clear function has yet been established. This research is starting to shed light on the molecular and biochemical basis of a number of neurodegenerative diseases of dramatic impact.

Protein Misfolding in Neurodegenerative Diseases: Mechanisms and Therapeutic Strategies addresses key issues concerning protein misfolding and aggregation in neurodegenerative diseases. Building on recent developments, including the recognition of protein misfolding as both a marker and a causal agent, the text presents the work of those who are actively pursuing more effective treatments, as well as preventative measures, and a possible cure. These include the use of molecular chaperones to control misfolding and novel pharmaceuticals, as well as the potential role of various inhibitors and NSAIDS.

A Comprehensive Multifaceted Examination of the Complex Causal Agents Implicated in Protein Misfolding

Divided into five sections, this groundbreaking text provides up-to-date accounts for Alzheimer's, Parkinson's, Huntington's, Amyotrophic Lateral Sclerosis and Transmissible Spongiform Encephalitis. It also explores the highly likelihood that multiple factors, including oxidative stress, play a role in these complex diseases.


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Product Details
  • ISBN-13: 9780849373107
  • Publisher: Taylor & Francis Inc
  • Binding: Hardback
  • Height: 234 mm
  • No of Pages: 596
  • Series Title: CRC Enzyme Inhibitors
  • Sub Title: Mechanisms and Therapeutic Strategies
  • Width: 156 mm
  • ISBN-10: 0849373107
  • Publisher Date: 01 Dec 2007
  • Edition: 1
  • Language: English
  • Returnable: Y
  • Spine Width: 32 mm
  • Weight: 1001 gr


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