Pathogenesis and Functional Pathways of WSSV-infected Shrimp" is an informative and comprehensive book written by A. Swathi that delves into the mechanisms of pathogenesis and functional pathways in shrimp infected with White Spot Syndrome Virus (WSSV). The book explores the intricate relationship between the virus and its host, specifically the shrimp's immune response, viral replication, and the resulting cellular responses such as apoptosis and necrosis.
The book covers the two types of immunity that are involved in the shrimp's defense against WSSV: innate and adaptive immunity. Innate immunity involves the shrimp's hemolymph and hemocytes, which are responsible for the production of antimicrobial peptides, cytokines, and chemokines, as well as the activation of Toll-like receptors and signal transduction pathways. Adaptive immunity, on the other hand, involves the production of specific antibodies and the activation of T and B lymphocytes.
The book also discusses the role of various pathways and systems such as the RNAi pathway, microRNA, autophagy, endoplasmic reticulum stress, oxidative stress, heat shock proteins, ubiquitin-proteasome system, mitogen-activated protein kinases, and the nuclear factor-κB, JNK, p38 MAPK, ERK, and PI3K-Akt pathways in the shrimp's response to WSSV infection.
Furthermore, the book covers the structural components of shrimp cells, such as the cytoskeleton and various types of cell junctions (tight junctions, gap junctions, adherens junctions, and desmosomes), as well as the extracellular matrix, and their roles in the pathogenesis of WSSV infection.
Lastly, the book discusses various approaches to the diagnosis, treatment, prevention, and vaccination of WSSV infection. The book draws on the latest research in the field and presents a comprehensive guide for students, researchers, and professionals in the field of aquaculture and marine biology.
