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Pathogenèse de Proteus mirabilis dans les infections urinaires

Pathogenèse de Proteus mirabilis dans les infections urinaires

          
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About the Book

Parmi les défis croissants en matière de santé publique, les maladies infectieuses occupent une place prépondérante, car elles sont à l'origine de millions d'invalidités et de décès dans le monde. Les infections des voies urinaires (IVU) sont les maladies infectieuses les plus répandues dans les établissements de santé et peuvent affecter n'importe quelle partie du système urinaire. Proteus mirabilis est le principal agent pathogène à l'origine des infections urinaires compliquées, en particulier celles liées aux cathéters. P. mirabilis possède un arsenal impressionnant de facteurs de virulence qui contribuent à sa pathogénicité. Il a été décrit que l'adhésion fimbriale, la formation de biofilms, la motilité flagellaire et la sécrétion de toxines y contribuent. Ces facteurs de virulence cruciaux de P. mirabilis sont à l'origine d'infections urinaires compliquées. Par conséquent, la modulation de ces régulateurs transcriptionnels des gènes de virulence est devenue une stratégie thérapeutique alternative pour atténuer la pathogénicité de P. mirabilis. Les plantes médicinales constituent une source précieuse pour rechercher des inhibiteurs de virulence contre P. mirabilis. Par ailleurs, le cathéter revêtu d'un antibiofilm offre pour la première fois un moyen de réduire l'infection et ses complications chez les utilisateurs de cathéters urinaires à long terme.


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Product Details
  • ISBN-13: 9786206536253
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Editions Notre Savoir
  • Height: 229 mm
  • No of Pages: 64
  • Spine Width: 4 mm
  • Width: 152 mm
  • ISBN-10: 6206536254
  • Publisher Date: 07 Oct 2023
  • Binding: Paperback
  • Language: French
  • Returnable: N
  • Weight: 104 gr


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