TEN miles north of the city of St. Louis, in the State of Missouri, forty years ago, on a pleasant plain, sloping off toward a murmuring stream, stood a large frame-house, two stories high; in front was a beautiful lake, and, in the rear, an, old orchard filled with apple, peach, pear, and plum trees, with boughs untrimmed, all bearing indifferent fruit. The mansion was surrounded with piazzas, covered with grape-vines, clematis, and passion flowers; the Pride of China mixed its oriental-looking foliage with the majestic magnolia, and the air was redolent with the fragrance of buds peeping out of every nook, and nodding upon you with a most unexpected welcome. The tasteful hand of art, which shows itself in the grounds of European and New-England villas, was not seen there, but the lavish beauty and harmonious disorder of nature was permitted to take its own course, and exhibited a want of taste so commonly witnessed in the sunny South. The killing effects of the tobacco plant upon the lands of "Poplar Farm," was to be seen in the rank growth of the brier, the thistle, the burdock, and the jimpson weed, showing themselves wherever the strong arm of the bondman had not kept them down. Dr. Gaines, the proprietor of "Poplar Farm," was a good-humored, sunny-sided old gentleman, who, always feeling happy himself, wanted everybody to enjoy the same blessing. Unfortunately for him, the Doctor had been born and brought up in Virginia, raised in a family claiming to be of the "F. V.'s," but, in reality, was comparatively poor. Marrying Mrs. Sarah Scott Pepper, an accomplished widow lady of medium fortune, Dr. Gaines emigrated to Missouri, where he became a leading man in his locality. Deeply imbued with religious feeling of the Calvinistic school, well-versed in the Scriptures, and having an abiding faith in the power of the Gospel to regenerate the world, the Doctor took great pleasure in presenting his views wherever his duties called him. As a physician, he did not rank very high, for it was currently reported, and generally believed, that the father, finding his son unfit for mercantile business, or the law, determined to make him either a clergyman or a physician. Mr. Gaines, Senior, being somewhat superstitious, resolved not to settle the question too rashly in regard to the son's profession, therefore, it is said, flipped a cent, feeling that "heads or tails" would be a better omen than his own judgment in the matter. Fortunately for the cause of religion, the head turned up in favor of the medical profession. Nevertheless, the son often said that he believed God had destined him for the sacred calling, and devoted much of his time in exhorting his neighbors to seek repentance.