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Mecanismos de prevenção do cancro com curcumina e (-) epicatechina

Mecanismos de prevenção do cancro com curcumina e (-) epicatechina

          
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About the Book

O cancro do pulmão é a principal causa de morte relacionada com o cancro a nível mundial. Para combater isto, foram realizados ensaios de prevenção do cancro do pulmão em países ocidentais, mas estes não tiveram sucesso por várias razões. A curcumina, isolada da planta Curcuma longa (Linn), foi investigada como sendo uma promissora prevenção do cancro. No entanto, os mecanismos exactos de acção da curcumina ainda não foram claramente elucidados. Estudámos a relação entre a expressão de GADD45 e GADD153 e a indução apoptótica nas células cancerosas do pulmão humano PC-9, e os resultados sugerem que a up-regulation do GADD45 e GADD153 pela curcumina é um mecanismo primordial na actividade anticancerígena da curcumina. Embora a curcumina seja amplamente investigada como agente preventivo do cancro, o principal problema é a sua baixa biodisponibilidade. Para conseguir uma prevenção eficaz do cancro com curcumina, estudámos os efeitos potenciadores da CE a partir do chá verde, com curcumina. Os nossos resultados actuais demonstraram pela primeira vez que a CE melhora significativamente a actividade de prevenção do cancro da curcumina.


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Product Details
  • ISBN-13: 9786202910750
  • Publisher: Edicoes Nosso Conhecimento
  • Binding: Paperback
  • Language: Portuguese
  • Returnable: N
  • Weight: 131 gr
  • ISBN-10: 6202910755
  • Publisher Date: 07 Sep 2021
  • Height: 229 mm
  • No of Pages: 80
  • Spine Width: 5 mm
  • Width: 152 mm


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