In South Sudan the LRA are attacking a village and force a young boy to attack a woman.
Sam Childers (Gerard Butler) is an alcoholic drug-using biker from Pennsylvania. On his release from prison, he finds that his wife (Michelle Monaghan) has given up her job as a stripper, because she has since accepted Christ as her saviour. Initially infuriated by his wife's decision, he returns to his routine of partying and using drugs like heroin with his fellow biker friend Donnie (Michael Shannon). One night while on a bender with Donnie, he almost kills a vagrant. He is shaken by the experience, and the day after allows his wife to persuade him to go to church with her, where he is eventually baptized and offered salvation.
Sam soon finds a stable job as a construction worker and later starts his own construction company. Later, on a missionary trip to Uganda to build homes for refugees, he asks one of the SPLA soldiers watching over them to take him on a trip to the north, to Sudan. The soldier warns him that it is a war zone, but at Sam's insistence they go. They arrive at a medical tent in Sudan. As the soldier moves off to talk to some people, Sam is roped in by a female doctor to help lift a lipless Sudanese woman onto the examination table. That night as they lay on their beds at the relief station, they hear noises outside, and when they look out, Sam and the soldier see large numbers of Sudanese children swarming around to sleep outside the building.
The soldier explains that their parents send them to sleep over here because it is safer than staying in their own village. Sam wakes up the children and gets as many as he can fit to sleep in their room for the night. The next day Sam and the soldier follow the children back to their village only to find that the LRA has burnt it down and killed their parents. One of the children runs after his dog and is killed by a hidden landmine. Sam cradles the dead child and cries. The experience traumatizes and changes Sam. After returning home, Sam has a "vision from God" and decides to build an orphanage for the children of South Sudan, as well as a church in his own neighborhood that will be "open to all" without judgement. After its completion he begins preaching at his church, and helps his old friend Donnie get sober and find God as well. He soon returns to Africa and despite vocal opposition, builds the orphanage. One night after it is built, the LRA attack it and burn it to the ground. Sam then phones home, telling his wife what has happened and that he is giving up. She reminds him that the orphans have been through worse but they have not given up, and that he should not give up and tells him to rebuild the orphanage. Sam returns home to the U.S. disgruntled and exasperated by the lack of money for the project. He also feels disconnected from his community; he is disgusted by displays of excess and the petty "problems" of his family and friends, as well as their apparent apathy toward the children of Sudan. Sam even goes far as to neglect his family and beat up a biker at a bar for making racist comments about the children. Meanwhile, his friend Donnie breaks his sobriety and ends up dying from an overdose. This pushes Sam further into negativity and despair. He sells his business and boards a plane for Sudan. His faith and mission is revitalized when an orphan boy tells his personal story to Sam. The boy tells him that if he allows hatred to fester in his heart, his fight against injustice fails. Sam also rekindles his emotional attachment with his family over the phone. The next day he engages with the camp actively. Later he goes out with SPLA and rescues a caravan full of children who were kidnapped by LRA. The end credits include black and white pictures of the real Sam Childers, his wife, daughter, and his orphanage in Sudan.
