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Lesioni cerebrali traumatiche: Implicazioni delle cellule staminali e della nanotecnologia

Lesioni cerebrali traumatiche: Implicazioni delle cellule staminali e della nanotecnologia

          
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About the Book

La lesione cerebrale traumatica (TBI) è un disturbo che distrugge le funzioni cerebrali e provoca gravi disturbi cognitivi ed emotivi. È una causa comune di mortalità e morbilità degli esseri umani a livello globale. Recenti ricerche hanno indicato che le cellule staminali mesenchimali (MSC) trapiantate sono in grado di migrare e di adattarsi ai siti cerebrali danneggiati per contribuire alla guarigione del tessuto cerebrale danneggiato. I meccanismi alla base dell'azione delle MSC sono le proprietà antiapoptotiche e antinfiammatorie di queste cellule, oltre alla loro capacità di rilasciare fattori neurotrofici e angiogenici. D'altra parte, lo scarso coinvolgimento del bersaglio da parte dei farmaci somministrati in seguito a TBI ha ampliato le opportunità di approcci basati su nanoparticelle (NP) per migliorare la somministrazione e la biodisponibilità dei farmaci in modo sito-specifico. Le strategie terapeutiche attraverso il sistema di rilascio delle NP hanno mostrato la promessa di mostrare un effetto neuroprotettivo, riducendo l'interruzione dell'unità neurovascolare e prevenendo l'espansione delle perturbazioni biochimiche al cervello sano adiacente.Questo libro discuterà principalmente gli aggiornamenti sulle più recenti modalità terapeutiche per la TBI sperando di stabilire le prove per il trattamento di questa patologia.


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Product Details
  • ISBN-13: 9786205933633
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Edizioni Sapienza
  • Height: 229 mm
  • No of Pages: 68
  • Spine Width: 4 mm
  • Weight: 113 gr
  • ISBN-10: 6205933632
  • Publisher Date: 25 Apr 2023
  • Binding: Paperback
  • Language: Italian
  • Returnable: N
  • Sub Title: Implicazioni delle cellule staminali e della nanotecnologia
  • Width: 152 mm


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