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Inmunología Pediátrica

Inmunología Pediátrica

          
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About the Book

A través de los años, la inmunología ha evolucionado hasta destacarse como un pilar fundamental para el entendimiento de multitud de enfermedades. Si re-flexionamos detenidamente, comprobaremos que la inmensa mayoría, sino todos los casos con los que nos enfrentamos diariamente tienen un componente inmuno-lógico fundamental: infecciones, alergias, autoinmunidades, cuadros inflamatorios agudos y crónicos, vacunaciones, etc., constituyen el caballo de batalla coti-diano de los pediatras.


Gracias a estos avances, en las últimas décadas la inmunología clínica ha tenido un enorme desarrollo y, como consecuencia de ello, se ha incrementado de forma muy significativa el número de enfermedades inmunitarias, infecciosas e incluso oncológicas que podemos diagnosticar y tratar. Un ejemplo lo constituye el vertiginoso cambio que se ha experimentado en el conocimiento de las inmunode-ficiencias primarias y secundarias, tanto de sus manifestaciones clínicas como en las posibilidades diagnósticas y terapéuticas. Estos cambios hacen necesario que el profesional a cargo de pacientes con IDP se mantenga constantemente actuali-zado. Los avances en el conocimiento, el manejo y la sobrevida de los pacientes con inmunodeficiencias, así como sus manifestaciones autoinmunes asociadas, requieren de profesionales con entrenamiento específico en dichas áreas, tanto en el ámbito pediátrico como en adultos. Por otra parte, y como pilar fundamental de la prevención de enfermedades infecciosas en individuos inmunocompetentes e inmunodeficientes, contamos con la valiosa herramienta que constituye la vacunación.


De acuerdo con el plan de acción mundial sobre vacunas de la Asamblea Mundial de la Salud, a pesar del incremento en la tasa de natalidad, la vacunación ha contribuido de forma indiscutible a reducir la cantidad de muertes anuales en niños menores de cinco años. Por lo tanto, las vacunas constituyen una de las medidas sanitarias que mayor beneficio ha producido y sigue produciendo a la humanidad. La meta de la vacunación es imitar la respuesta inmune que provoca la infección natural, evocando mecanismos similares a los que ocurren durante esta. Los permanentes avances en el campo de la vacunología aplicados a programas de inmunoprofilaxis han logrado mejorar notablemente la efectividad y la seguridad de las inmunizaciones, garantizando la activación de la memoria inmunológica y la ausencia de efectos colaterales indeseables. El conocimiento cada vez más exhaustivo de los mecanismos inmunológicos de las enfermedades infecciosas está sirviendo para la producción de mejores vacunas. Con base en este conocimiento y en la epidemiología de cada enfermedad, las pautas de vacunación han ido variando con el tiempo. Así, por ejemplo, vamos introduciendo nuevas vacunas en el calendario, como la tetravalente de meningococo, establecemos catch up para otras donde es posible que hayamos perdido memoria inmunitaria o incluso, como es el caso de la vacuna HPV, ya se discute si la pauta vacunal monodosis es suficiente. Alguien decía que para actuar sobre un sistema de forma correcta lo primero que había que hacer era conocer el sistema en profundidad. Es por ello por lo que hemos dedicado el primer bloque del libro a conocer estos mecanismos en relación con el niño, para seguir con un segundo bloque más clínico, donde se abordan las cada vez más frecuentemente diagnosticadas inmunodeficiencias primarias y secundarias, y finalmente pasar a un tercer y último bloque dedicado a la inmunoprofilaxis activa/vacunación de las enfermedades infecciosas atendiendo, tanto desde un punto de vista básico como clínico, todo lo referente a las enfermedades infecciosas infantiles inmunoprevenibles.


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Product Details
  • ISBN-13: 9788417403607
  • Publisher: Amazing Books S.L.
  • Publisher Imprint: Amazing Books S.L.
  • Height: 244 mm
  • No of Pages: 706
  • Spine Width: 38 mm
  • Width: 170 mm
  • ISBN-10: 8417403604
  • Publisher Date: 04 Apr 2022
  • Binding: Hardback
  • Language: Spanish
  • Returnable: N
  • Weight: 1314 gr


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