The Virginia 21st Cavalry Regiment was organized in August, 1862, with companies which had served in the Virginia State Line. The unit was assigned to W.E. Jones' and McCausland's Brigade along with the 14th, 16th, and 17th Virginia Cavalry and in April, 1864, it contained 317 effectives. It took an active part in various conflicts in East Tennessee, western Virginia, and in the Shenandoah Valley. During mid-April, 1865, the regiment disbanded. Companies
Company A (Captains Stephen P. Halsey, George R. Appleby, Charles A. Calhoun & William H. Balthis) - many men from Company F, 4th Regiment Virginia State Line
Company B (Captains David Edmundson, Charles Burks, Jackson Moore) - many men from Company I, 4th Regiment, Virginia State Line
Company C 2nd(Initially called (1st) Company G) - Many men from Washington County
Company D 2nd(Captains John Alexander Logan & William H. Francis)
Company E 1st (from Company B, 2nd Regiment Virginia State Line) - many men from Russell County
Company E 2nd (formerly called 1st Company I) Captains: C. F. McDanold, William M. Cox
Company F (Captain Frederick T. Gray) - many men from Washington County
Company G 2nd (Captain Armistead O.Dobyns) - many men from Floyd County, other counties represented were Franklin, Patrick and Henry County
Company H (Captain John Calhoun Summers) - Officers of this company were captured and company records were lost.
Company I (2nd) (Formerly called Company C, Captains: William J. Pasley, Alexander L. Halsey, M. V. B.Norman)
Company K (Initially called (1st) Company D) Captains: John Mayo Oliver, Andrew R. Humes
Captain Robert H. Gleaves' Company (Disbanded and members were transferred to Company K)
Captain C. C. Pack's Company: (Mustered into the 21st Cavalry, then was assigned to the 37th Battalion Virginia Cavalry)
