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Handbook of Falciparum Malaria

Handbook of Falciparum Malaria

          
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About the Book

All-in-all a great compendium provides all aspects of Malaria from the epidemiology to preventive strategies.
Provides extensive material on the subject for the treatment of critically ill patient suffering from Malaria.
A must-read book for any postgraduate from the field of medicine, pathology, microbiology, paediatrics, community medicine, and obstetrics & gynecology.
Must on the desk for all physicians in the tropical countries.

Table of Contents:
1. Overview of Malaria 1 Dhwanee Thakkar, Anupam Sachdeva, Nita Radhakrishnan • Etiology 1 • Epidemiology 2 2. Etiology of Plasmodium falciparum 10 Chand Wattal, Neeraj Goel The Causative Organism 10 3. Pathogenesis of Plasmodium falciparum 16 Anju Nijhawan Induction of Fever by Malaria Parasite 20 4. Clinical Features of Malaria 26 Tarangini D, Nita Radhakrishnan, Anupam Sachdeva • Incubation Period 26 • Uncomplicated Malaria 27 • Complicated Malaria 27 • Other Manifestations of Malaria 31 5. Falciparum Malaria in Adults 33 Tarangini D, Nita Radhakrishnan, Anupam Sachdeva • Characteristics of Falciparum Malaria 33 • Laboratory Findings 35 6. Cerebral Malaria 37 Tarangini D, Sandeep Dhingra, Anupam Sachdeva • Pathogenesis 37 • Clinical Manifestations 39 • Management 41 • Never Give Bolus Injection of Quinine 42 Prelims.indd 11 09-04-2014 17:45:18 xii Handbook on Falciparum Malaria 7. Hypoglycemia in Children with Malaria 46 Shirali Aggarwal, Roop Sharma, Anupam Sachdeva • Definition of Hypoglycemia 47 • The Influence of Age and Fasting on Glucose 47 • Gluconeogenesis 49 • Glucose Metabolism In Malaria and Other Infectious Diseases 50 • Glucose Production and Uptake in Infectious Disease 51 • Gluconeogenesis in Infectious Disease 53 • Glycogenolysis in Infectious Disease 53 • Antimalarials and Hypoglycemia 55 8. Renal Failure in Falciparum Malaria 62 Vinant Bhargava, Dinesh Khullar • Epidemiology 62 • Life Cycle 63 • Clinical Characteristics 63 • Pathophysiology 64 • Histology 66 • Prognosis 69 • Treatment 70 9. Hematological Manifestations of Malaria 79 Nivedita Dhingra, Anupam Sachdeva • Anemia 79 • White Cell, Platelet, and Coagulation Changes in Acute Malaria Infection 82 • Hemophagocytic Lymphohistiocytosis 83 • Hyper-reactive Malarial Splenomegaly Syndrome 83 10. Malarial Hepatitis 85 Piyush Ranjan • Epidemiology of Jaundice in Malaria 85 • Pathogenesis of Jaundice in Malaria 86 • Histopathology of Liver Involvement in Malaria 89 Prelims.indd 12 09-04-2014 17:45:19 xiii Contents 11. Pulmonary Edema in Malaria 94 Shirali Aggarwal, Preeti Anand, Nita Radhakrishnan • Respiratory Complications of Malaria 95 • Clinical Features 96 • Treatment 98 12. Multiorgan Dysfunction Syndrome in Malaria 102 Payal Malhotra, Manas Kalra, Anupam Sachdeva • Criterion of SIRS in Pediatric Population 103 • Criterion of SIRS in Adults/Adolescents 104 • Pathophysiology of MODS in Malaria 104 • Predictors of MODS in Malaria 106 13. Falciparum Malaria in Pregnancy 108 Indrani Ganguli, Mamta Dagar • Pathogenesis 109 • Prevalence, Microbiology, and Epidemiology 109 • Clinical Manifestations 110 • HIV Coinfection 112 • Diagnosis 112 • Outcome 113 • Treatment of Malaria and Management of Pregnancy 114 • Summary and Recommendations for Obstetric Management Specific to Malaria Infection in Pregnancy (RCOG Green —Top Guideline) 117 14. Falciparum Malaria in Children: A Changing Paradigm 120 Payal Malhotra, Manas Kalra, Nita Radhakrishnan • Manifestation of Malaria in Pediatric Population 121 • Symptoms and Signs in Malaria 121 • Complications in Children 124 • A Decade of Progress in Malaria Control 125 • UNICEF’s Contributions to Malaria Control 125 • Funding Gap 125 Prelims.indd 13 09-04-2014 17:45:19 xiv Handbook on Falciparum Malaria 15. Transfusion-transmitted Plasmodium falciparum Malaria 126 RN Makroo • Plasmodium falciparum: Life Cycle, Pathogenesis and Clinical Features 127 • Epidemiology 131 16. Laboratory Diagnosis of Falciparum Malaria 141 Shalini Duggal, Tulsi Das Chugh Diagnostic Methods of Falciparum Malaria 141 17. Serological Diagnosis of Falciparum Malaria 159 Tulsi Das Chugh, Shalini Duggal • Conventional Serological Tests 159 • Rapid Diagnostic Tests 160 18. Uncomplicated Malaria 170 Payal Malhotra, Vipan Kumar Goyal, Manas Kalra, Nita Radhakrishnan • P. falciparum or Species not Identified: Acquired in Areas without Chloroquine-resistance 170 • P. falciparum or Species not Identified: Acquired in Areas with Chloroquine-resistance 171 • Alternatives for Pregnant Women 176 19. Treatment of Severe Falciparum Malaria 178 Anand Kumar K, Aditya Kumar Gupta, Nita Radhakrishnan, Anupam Sachdeva • Diagnosis 178 • Management 179 • General Measures 179 • Specific Treatment 180 20. Treatment of Mixed Infections in Malaria 183 Payal Malhotra, Rahul Arora, Anupam Sachdeva • Treatment of Mixed Infections 184 • Rationale of Using Combination Therapy in Mixed Infections 184 • Artemisinin-based Combination Therapy 185 • Nonartemisinin-based Combinations 188 Prelims.indd 14 09-04-2014 17:45:19 xv Contents 21. Malaria Vaccines: Current Scenario 190 Vasant Chinnabhandar, Anupam Sachdeva • Malaria Vaccines: Rationale and Challenges 192 • Vaccines Against Malaria—Main Groups 193 • Role of Adjuvants 197 • Current Status and Immediate Future 198 22. National Malaria Control Programme 200 Anand Kumar K, Aditya Gupta, Nita Radhakrishnan • National Vector Borne Disease Control Programme 201 • Functioning of National Vector Borne Disease Control Programme 201 • Strategic Action Plan 2007 203 23. Prevention Strategies of Malaria 214 Anand Kumar K, Aditya Kumar Gupta, Anupam Sachdeva • Antimalarial Drugs 214 • Mosquito Vector Control 215 • Personal Protection from Infection 217 • Prevention of Malaria Infection in Travelers 217 • Relapse Prevention 222 • Pregnant Travelers 222 • Children 223 Index 225 Prelims.indd 15 09-04-2014 17:45:19


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Product Details
  • ISBN-13: 9789351523079
  • Publisher: Jaypee Brothers Medical Publishers Pvt. Ltd.
  • Publisher Imprint: Jaypee
  • Edition: 1
  • Language: English
  • Width: 159 mm
  • ISBN-10: 9351523071
  • Publisher Date: 2015
  • Binding: Paperback
  • Height: 241 mm
  • No of Pages: 248


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