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Formulation Et Évaluation Des Patchs Transdermiques

Formulation Et Évaluation Des Patchs Transdermiques

          
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About the Book

L'administration de médicaments par voie transdermique présente plusieurs avantages par rapport à d'autres voies d'administration. Un patch transdermique est un patch adhésif médicamenteux qui est placé sur la peau pour délivrer une dose de médicament à libération progressive à travers la peau pour le traitement d'une maladie systémique. Le système thérapeutique transdermique revêt une importance clinique particulière pour la prévention et le traitement à long terme de maladies chroniques telles que la polyarthrite rhumatoïde, l'arthrose, la spondylarthrite ankylosante, la dysménorrhée, la goutte aiguë et la douleur. Les avantages de l'utilisation d'un système d'administration transdermique des médicaments comprennent une meilleure biodisponibilité systémique résultant du contournement du métabolisme hépatique de premier passage. Le traitement peut également être interrompu rapidement en retirant simplement le patch chaque fois que cela est nécessaire. L'objectif du développement de nouveaux dispositifs d'administration de médicaments par voie transdermique est d'obtenir une entrée contrôlée, prévisible et reproductible du médicament dans la circulation sanguine du patient. Le dispositif transdermique agit comme un réservoir et contrôle le taux de transfert du médicament. Lorsque le flux de médicament transdermique est contrôlé par le dispositif plutôt que par la peau, l'administration du médicament est plus reproductible, ce qui permet de réduire les variations inter et intra-sujet en raison de la libération du médicament par le dispositif.


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Product Details
  • ISBN-13: 9786205966440
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Editions Notre Savoir
  • Height: 229 mm
  • No of Pages: 72
  • Spine Width: 4 mm
  • Width: 152 mm
  • ISBN-10: 6205966441
  • Publisher Date: 22 May 2023
  • Binding: Paperback
  • Language: French
  • Returnable: N
  • Weight: 118 gr


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