Table of Contents
Preface
Contributors
I. The Problem and Available Resources
1. Introduction to Evidence-Based Pathology and Laboratory Medicine Alberto M. Marchevsky and Mark Wick
. Evidence-Based Pathology: A Stable Set of Principles for a Rapidly Evolving Specialty
José Costa and Sarah Whitaker
3. What Is Best Evidence in Pathology?
Peter J. Saunders and Christopher N. Otis
4. Biostatistics 101
Robin T. Vollmer
5. Prognostication and Prediction in Anatomic Pathology: Carcinoma of the Breast as an Illustrative Model
Mark R. Wick and Alberto M. Marchevsky
6. Principles of Classification and Diagnosis in Anatomic Pathology and the Inevitability of Problem Cases
Michael Hendrickson
7. Evaluating Oncopathological Studies: The Need to Evaluate the Internal and External Validity of Study Results
Michael Hendrickson and Bonnie Balzer
8. Power Analysis and Sample Sizes in Pathology Research
Robin T. Vollmer
9. Meta-Analysis: A Statistical Method to Integrate Information Provided by Different Studies
Eleftherios C. Vamvakas
10. Decision Analysis and Decision Support Systems in Anatomic Pathology
Michael Hendrickson and Bonnie Balzer
II. Solutions Offered by Evidence-Based Pathology and Laboratory Medicine11. Evidence-Based Approach to Evaluate Information Published in the Pathology Literature and Integrate It with Personal Experience Alberto M. Marchevsky and Mark Wick
12. Evidence-Based Cell Pathology Re-visited: A Personal View
Kenneth Fleming
13. Development of Evidence-Based Diagnostic Criteria and Prognostic/Predictive Models: Experience at Cedars Sinai Medical Center
Alberto M. Marchevsky and Ruta Gupta
14. Evaluation and Reduction of Diagnostic Errors in Pathology Using an Evidence-Based Approach
Raouf E. Nakhleh
15. Metaanalysis 101 for Pathologists
Ruta Gupta and Alberto M. Marchevsky
16. Evidence-Based Practices in Applied Immunohistochemistry: Dilemmas Caused by Cross-Purposes
Mark R. Wick, Paul E. Swanson, and Alberto M. Marchevsky
17. Evidence-Based Pathology and Laboratory Medicine in the Molecular Pathology Era: Transition of Tests from the Research Bench into Practice
Jia-Perng Jennifer Wei and Wayne W. Grody
18. The Use of Decision Analysis Tools for the Selection of Clinical Laboratory Tests: Developing Diagnostic and Forecasting Models Using Laboratory Evidence
Ji Yeon Kim, Elizabeth M. Van Cott, and Kent B. Lewandrowski19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support Systems
Stacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic
20. Evidence-Based Pathology and Tort Law: How Do They Compare?
Mark R. Wick and Elliott Foucar
Index
