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Endokrine Ophthalmopathie

Endokrine Ophthalmopathie

          
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About the Book

Man darf es als ein Ergebnis der durch die Methoden des Laboratorium vertieften klinischen Forschung bezeichnen, daß die eine Hyperthyreose be- gleitenden Augenerscheinungen keineswegs obligatorisch sind und daß diese "endokrine Ophthalmopathie" häufig auch außerhalb des Bereichs der Hyper- thyreose, d. h. bei euthyreoten Patienten beobachtet wird. Mit dieser hyper- thyreoten und euthyreoten endokrinen Ophthalmopathie, einem ernsten, oft progredienten Leiden, hat sich der Verfasser seit vielen Jahren klinisch und experimentell befaßt. Schon seit längerer Zeit war klar, daß der Hypo- physenvorderlappen bei der Genese eine Rolle spielen müsse, da Augen- symptome niemals angetroffen werden, wenn die Hyperthyreose ohne Beteiligung der Hypophyse entsteht, z. B. beim toxischen Adenom und bei der Hyperthyreosis factitia. Der experimentelle Nachweis des im Serum vor- handenen Exophthalmus produzierenden Faktors und weitere Kriterien ermöglichen es, die endokrine Ophthalmopathie von ähnlichen, nicht endo- krin bedingten ophthalmologischen Krankheitsprozessen abzugrenzen. Ein weiteres Anliegen des Verfassers war es, den erwähnten humoralen Faktor vom Thyreotropin und dem "Long-Acting Thyroid Stimulator" abzutrennen. Gleichzeitig stellen die Untersuchungen einen Beitrag zur Erkenntnis der Pathogenese der Hyperthyreose dar und zeigen die therapeutischen Möglich- keiten für die endokrine Ophthalmopathie auf. Die vorliegende Monographie, die aus der Habilitationsarbeit des Ver- fassers hervorgegangen ist, versucht, die für die Klinik so überaus wichtige Verbindung zwischen Tierexperiment und klinischer Beobachtung herzustel- len. Das große Krankengut der Klinik und des Schilddrüsenambulatoriums, das vom Verfasser selbst untersucht wurde, konnte dieser Arbeit nutzbar gemacht werden. Bei den tierexperimentellen Untersuchungen kam dem Verfasser seine frühere pharmakologische Tätigkeit zugute.


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Product Details
  • ISBN-13: 9783662218754
  • Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
  • Binding: Paperback
  • Height: 234 mm
  • No of Pages: 108
  • Series Title: Experimentelle Medizin, Pathologie Und Klinik
  • Weight: 173 gr
  • ISBN-10: 3662218755
  • Publisher Date: 20 Nov 2013
  • Edition: Softcover Reprint of the Origi ed.
  • Language: German
  • Returnable: N
  • Spine Width: 6 mm
  • Width: 156 mm


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