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Eine kritische Betrachtung einer überhöhten Eisenzufuhr durch Nahrung und Supplemente

Eine kritische Betrachtung einer überhöhten Eisenzufuhr durch Nahrung und Supplemente

          
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About the Book

Inhaltsangabe: Einleitung: In dieser Arbeit soll zunächst der physiologische Eisenstoffwechsel beschrieben werden. Dabei liegt der Schwerpunkt auf der Erörterung der Steuerung der Eisenabsorption im Duodenum und der Regulation der Eisenhomöostase auf zellulärer Ebene. Anschließend wird näher auf verschiedene Formen der Eisenspeichererkrankungen eingegangen, wobei die genaue Beschreibung der sogenannten Typ 1 Hämochromatose im Vordergrund steht. Nach einer kurzen Beschreibung der möglichen Mechanismen der toxischen Wirkungen von Eisen werden die Zusammenhänge zwischen Eisenstatus und verschiedenen Erkrankungen, wie etwa jenen des Herz-Kreislauf-Systems, aufgezeigt. Nachfolgend werden aktuelle Diagnose- und Therapieverfahren bei Eisenüberladungszuständen angeführt. Schließlich ist das Ziel der Arbeit die Einschätzung, ob in den westlichen Industrieländern eine Eisenüberversorgung durch Ernährung möglich ist, und welche negativen Auswirkungen diese auf die Gesundheit der betroffenen Menschen haben könnte. Außerdem soll im letzten Abschnitt der vorliegenden Arbeit die Einnahme von Eisensupplementen kritisch betrachtet werden. Inhaltsverzeichnis: Inhaltsverzeichnis: 1.EinleitungI 2.Der Eisenstoffwechsel2 2.1Chemie von Eisen2 2.2Vorkommen von Eisen2 2.3Eisenproteine3 2.3.1Hämproteine3 2.3.2Nichthäm-Eisen-Proteine5 2.4Digestion und Resorption eisenhältiger Nahrungsmittel7 2.4.1Aufnahme aus dem Darmlumen in die Mukosazelle und proteinvermittelter intrazellulärer Transport8 2.4.1.1Regulation der Eisenabsorption der intestinalen Villi des Duodenums9 2.4.2Abgabe an das Eisentransportsystem des Blutplasmas11 2.5Eisenaufnahme in somatische Zellen12 2.5.1Intrazelluläre Eisenspeicherung15 2.6Regulation der Eisenhomöostase17 2.6.1Posttranskriptionelle Regulation des Eisenstoffwechsels durch IRPs18 2.6.2Modulation der IRP/IRE-Interaktion durch NO20 2.6.3Zusammenhänge zwischen Energie- und Eisenstoffwechsel22 2.7Eisenbestand und Eisenumsatz27 2.8Hämog


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Product Details
  • ISBN-13: 9783838671727
  • Publisher: Diplom.de
  • Binding: Paperback
  • Language: German
  • Returnable: N
  • Spine Width: 8 mm
  • Width: 148 mm
  • ISBN-10: 3838671724
  • Publisher Date: 01 Sep 2003
  • Height: 210 mm
  • No of Pages: 136
  • Series Title: German
  • Weight: 190 gr


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Eine kritische Betrachtung einer überhöhten Eisenzufuhr durch Nahrung und Supplemente
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