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Effets Du Remicade(r) Sur Le Si Au Cours de la Polyarthrite Rhumatoïde

Effets Du Remicade(r) Sur Le Si Au Cours de la Polyarthrite Rhumatoïde

          
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About the Book

Depuis 1993, le REMICADE(R), agent modulant le TNF-, semble prendre une place majeure dans le traitement de la PR. Nous avons étudié les effets du REMICADE(R) à long terme chez des patients atteints de PR, sur le plan biologique, par l'étude des marqueurs classiques de l'inflammation (VS, PCR) et d'un marqueur plus particulier la MMP-3, ainsi que sur le plan immunologique, par l'étude des différents auto-anticorps présents au cours de la PR. Nos résultats ont montré que le REMICADE(R) entraînait une diminution très rapide des marqueurs de l'inflammation et en particulier de la MMP-3, indiquant que le REMICADE(R) neutralise plus spécifiquement l'inflammation au niveau articulaire. Le REMICADE(R) entraîne une augmentation des anticorps anti-nucléaires et l'apparition d'anticorps anti-ADN, il n'a aucun effet sur les anticorps anti-peptides cycliques citrullinés dont le dosage est plus un élément de diagnostic. Le suivi des malades atteints de PR, sous traitement par REMICADE(R), est indispensable pour évaluer à long terme l'efficacité de ce nouveau médicament qui pose un problème économique vu son coût élevé.


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Product Details
  • ISBN-13: 9783838189727
  • Publisher: Academiques
  • Binding: Paperback
  • Language: French
  • Returnable: N
  • Spine Width: 9 mm
  • Width: 152 mm
  • ISBN-10: 3838189728
  • Publisher Date: 28 Feb 2018
  • Height: 229 mm
  • No of Pages: 160
  • Series Title: Omn.Pres.Franc.
  • Weight: 245 gr


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