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Drug Trial Secrets: How Drug Companies and Medical Experts Dupe You and Your Doctor

Drug Trial Secrets: How Drug Companies and Medical Experts Dupe You and Your Doctor

          
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About the Book

Drug Trial Secrets tells the story of the most famous clinical drug trial of all time -- the only trial to lead to a fraud charge, as well as the biggest drug company fine in history.

GlaxoSmithKline paid for Study 329, the clinical trial of their antidepressant Paxil (paroxetine) in the 1990s, and the resulting research was published in the Journal of the American Association of Child Adolescent Psychiatry. The article claimed the drug was effective and safe -- even though GSK knew from the research that Paxil didn't work for children and was harmful. In 2004, New York State charged the company with fraud because of this publication. It wouldn't be until 2012 when the Department of Justice also charged GSK with fraud and failure to report safety data that GSK settled and paid a giant $3 billion fine.

But perhaps the most important result was that independent researchers were given access to the full, original records of the clinical trial and relating documents. David Healy and his co-authors spent thousands of hours re-analyzing the raw data, and in this book they describe exactly how GSK and the medical professionals who claimed authorship of the journal article manipulated the data to produce the false result they wanted. They also document the battle they finally won to get the British Medical Journal to publish a re-write of the original study -- thirteen years later!

A gripping true-crime narrative, Drug Trial Secrets will leave readers with many questions about the reliability of drug company trials and research by medical professionals funded by drug companies.


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Product Details
  • ISBN-13: 9781459413108
  • Publisher: Formac Publishing Company Limited
  • Publisher Imprint: Lorimer
  • Height: 229 mm
  • No of Pages: 224
  • Spine Width: 13 mm
  • Weight: 100 gr
  • ISBN-10: 1459413105
  • Publisher Date: 01 Apr 2023
  • Binding: Paperback
  • Language: English
  • Returnable: Y
  • Sub Title: How Drug Companies and Medical Experts Dupe You and Your Doctor
  • Width: 152 mm


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