1. Volume Overview - Introduction
Craig Harris
2. In Vivo Models of Developmental Toxicology
Jason M. Hansen
3. Caenorhabditis Elegans as a Model in Developmental Toxicology
Windy A. Boyd, Marjolein V. Smith, and Jonathan H. Freedman
4. Zebrafish Embryo Developmental Toxicology Assay
Julieta M. Panzica-Kelly, Cindy X. Zhang, Karen Augustine-Rauch
5. Gene Knockdown by Morpholino-modified Oligonucleotides in the Zebrafish (Danio rerio) Model: Applications for Developmental Toxicology
Alicia R. Timme-Laragy, Sibel I. Karchner, Mark E. Hahn
6. An Amphibian Model for Studies of Developmental Reproductive Toxicity
Cecilia Berg
7. Avian Models in Teratology and Developmental Toxicology
Susan M. Smith, George R. Flentke, Ana Garic
8. Overview of In Vitro Models in Developmental Toxicology
Craig Harris
9. Primary Cell and Micromass Culture in Assessing Developmental Toxicity
M Pratten, Bhavesh K. Ahir, H. Smith-Hurst, S Memon, P Mutch & P.Cumberland
10. Embryonic Stem Cell Test (EST): Stem cell Use in Predicting Developmental Cardiotoxicity and Osteotoxicity
Béatrice Kuske, Polina Y. Pulyanina, Nicole I. zur Nieden
11. Mouse Embryonic Stem Cell Adherent Cell Differentiation and Cytotoxicity (ACDC) Assay
Marianne Barrier, Kelly Chandler, Susan Jeffay, Maria Hoopes, Tom Knudsen, Sid Hunter
12. The Murine Limb Bud in Culture as an In Vitro Teratogenicity Test System
France-Hélène Paradis, Chunwei Huang and Barbara F. Hales
13. Rodent Whole Embryo Culture
Craig Harris
14. Rabbit Whole Embryo Culture
Valeris A. Marshall and Edward W. Carney
15. Assessment of Xenobiotic Biotransformation Including Reactive Oxygen Species Generation in the Embryo using Benzene as an Example
Helen J. Renaud, Allison Rutter, and Louise M. Winn
16. Methodological Approaches to Cytochrome P450 Profiling in Embryos
Jared V. Goldstone and John J. Stegeman
17. Analysis of Nrf2-Mediated Transcriptional Induction of Antioxidant Response in Early Embryos
Shao-yu Chen
18. Regulation and Control of AP-1 Binding Activity in Embryotoxicity
Terence R.S. Ozolins
19. Thioredoxin Redox Status Assessment During Embryonic Development: The Redox Western
Jason M. Hansen
20. Methods for the Determination of Plasma or Tissue Glutathione Levels
Trent E. Tipple and Lynette K. Rogers
21. Oxidative Stress, Thiols, and Redox Profiles
Craig Harris and Jason M. Hansen
22. A Review of Toxicogenomic Approaches in Developmental Toxicology
Joshua F. Robinson, Jeroen L.A. Pennings, Aldert H. Piersma
23. Epigenetic Approaches and Methods in Developmental Toxicology: Role of Inhibition in Teratogenic Events
Elena Menegola, Graziella Cappelletti and Francesca Di Renzo
24. DNA Methylation Screening and Analysis
Karilyn E. Sant, Muna S. Nahar, and Dana C. Dolinoy
25. Assessment of Histiotrophic Nutrition using Fluorescent Probes
Jeffrey Ambroso and Craig Harris
26. Diabetic Embryopathy
Ulf J. Eriksson and Parri Wentzel
27. Gene Expression Analysis in Developing Embryos: In situ Hybridization
Siew-Ging Gong
28. Assessment of Gross Fetal Malformations: The Modernized Wilson Technique and Skeletal Staining
BRobert E. Seegmiller, Nathan Cook, Korance Goodwin, and Timothy Leishman
