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Development of the Perineum in the Human: A Comprehensive Histological Study with a Special Reference to the Role of the Stromal Components

Development of the Perineum in the Human: A Comprehensive Histological Study with a Special Reference to the Role of the Stromal Components

          
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About the Book

References. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 126 Subject Index. . . . . . . . . . . . . . . . . . . . . . . . . . . . 133 1 Introduction The developmental steps which lead to the formation of the human perineum seem firmly established (Arey 1965; Hamilton and Mossman1972; Moore and Persaud 1998; Wartenberg 1993; Sadler 1995; Larsen 1997). They form the base for the evaluation of the pathogenesis of a great variety of complicated and often serious malformations which occur in this region. This concept has, however, been challenged by the results of an investigation into the n- mal and abnormal development of the anorectum in pig (van der Putte and Neeteson 1983, 1984; van der Putte 1986). Observations revealed that at least in pig, a major element in current ideas about the early development of the perineum, namely the process by which the original simple cloaca is sub- vided into a urogenital and anal part is incorrect, while additional obser- tions strongly suggested that the same may be true for ideas about female and male sexual transformation. A preliminary investigation in human - bryos gave similar indications (van der Putte 1986). The data supported e- lier critical findings (Politzer 1931, 1932; Wijnen 1964; Ludwig 1965) which have apparently been ignored, possibly because they seemed to hinder the understanding of the pathogenesis of congenital malformations such as - perforate anus and hypospadias.


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Product Details
  • ISBN-13: 9783540210399
  • Publisher: Springer
  • Publisher Imprint: Springer
  • Edition: 2005 ed.
  • Language: English
  • Returnable: Y
  • Spine Width: 5 mm
  • Weight: 217 gr
  • ISBN-10: 3540210393
  • Publisher Date: 01 Nov 2004
  • Binding: Paperback
  • Height: 236 mm
  • No of Pages: 136
  • Series Title: Advances in Anatomy, Embryology and Cell Biology
  • Sub Title: A Comprehensive Histological Study with a Special Reference to the Role of the Stromal Components
  • Width: 155 mm


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Development of the Perineum in the Human: A Comprehensive Histological Study with a Special Reference to the Role of the Stromal Components
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