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Detección de E6 y E7 de VPH mediante PCR

Detección de E6 y E7 de VPH mediante PCR

          
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About the Book

En los últimos años se han obtenido datos de investigaciones epidemiológicas y moleculares que demuestran que el Virus del Papiloma Humano (VPH) está asociado a las primeras etapas de Cáncer de Cuello Uterino. Estudios revelan que el VPH tiene un genoma de 7200-8000 pb con un tamaño de 45-55 nm de diámetro y una cápside icosaédrica compuesta por 72 capsómeros que rodean al genoma. El genoma se divide en tres regiones; una región temprana E (Early) la cual codifica para las proteínas virales (E1, E2, E4, E5, E6 y E7), una región tardía L (Late), que codifica para proteínas estructurales de la cápside (L1 y L2), y una región reguladora conocida como región larga de control LCR (Long Control Región). Esta investigación se enfoca en detección de regiones oncogénicas E6 y E7 que están relacionadas a la codificación y sobreexpresión de oncoproteínas. En el análisis se utilizó la PCR diseñando cebadores genéricos para L1 y L2, y principalmente para regiones E6 y E7 altamente conservadas y específicas.


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Product Details
  • ISBN-13: 9786202140270
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Editorial Academica Espanola
  • Height: 229 mm
  • No of Pages: 60
  • Spine Width: 4 mm
  • Width: 152 mm
  • ISBN-10: 6202140275
  • Publisher Date: 28 May 2018
  • Binding: Paperback
  • Language: Spanish
  • Returnable: N
  • Weight: 100 gr


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