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Corona Virus Now a current Public Health issue and a possible molecular solution for research Scientists.: A Possible Molecular Solution

Corona Virus Now a current Public Health issue and a possible molecular solution for research Scientists.: A Possible Molecular Solution

          
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About the Book

The cure of Coronavirus lies in molecular Biology of DNA of the virus its self. In bio-chemical terms, the Corona Virus is a transmitter of viral RNA (vRNA), specifically cRNA. The disease associated with it is COVID-19; a zoonotic pathogen called Betacoronavirus genus, originating from bats.SARS-CoV-2 uses the ACE2 receptor in Human Beings to tri-anchor infection onto human cells.SARS-CoV-2 shares some symptoms with the IAV (Influenza A virus), both are contagious (transmittable viruses), and cause respiratory illnesses. IAV is a promoter and primer of transcription by enveloping (E Protein) between Non-Coding Regions (NCR's) Membrane Glyco-Proteins (M) which are flanked at both ends, being bound by the protein enhancing Hemagglutinin Esterease Dimer (HE) the viral RNA (vRNA) and cap snatching (the Thymine), by pairing with Adenine, causing the Cytosine (the protein which pairs with Guanine) to be dropped at the stem loop.IAV is replicated when it is inside of the host cell nucleus, and the Negative-Sense viral RNA (vRNA) is in a relationship with the vRNA dependent Polymerase Complex. This replication creates a template for transcribing a replication, which is translated into Positive-Sense mRNA and cRNA. The virus has spread rapidly since February 17, 2020, 2019-nCoV has caused 71331 human infections and 1775 deaths in China and 24 other countries. Both (Lamont and Mbabazi, 2020) stipulate that RNA is transcribed from human genetic material (DNA), which means it can naturally occur. When viral mRNA is transcribed it is translated into viral proteins, which reads as the viral genome sequence of AGCU.In genetic sequencing, the G (Guanine) and the C (Cytosine) always pair, as they are the base pairs that create LIFE. (A)Adenine and (U) Uracil naturally pair, but the Uracil acts as an Envelope (E), breaking the connection between the (A) Adenine and (T) Thymine; these are the Nucleotides required to pair for LIFE to exist. When the (A) Adenine is enveloped, the structure begins to fall apart and the Nucleotide (T) Thymine gets pulled away, this leaves only the (U) Uracil which is enveloping the (A) Adenine. So to avoid the cell being allowed to die, the gaps are replaced with NCR's (Non-Coding Regions) made up from the base pairs to save life. In IVA the (S) Spike Protein is a (G) Guanine Protein. These (S) Spike Protein then replicate via these strands into Positive cRNA intermediates, and for viral mRNA syntheses, it requires Cellular RNA polymerase complex. So, in a nutshell, viral mRNA relies fully on polymerase complex cRNA (aka Corona Virus) to synthesize. If a vaccine was being considered, it would make logical sense to reverse this process in a lab setting, however such a task will not be a simple one. However, it is also significant that research must direct its efforts towards developing a vaccine in order to assist the human immune system in its attempt to destroy the coronavirus once it has gained entry into the host.


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Product Details
  • ISBN-13: 9798618850445
  • Publisher: Independently Published
  • Publisher Imprint: Independently Published
  • Height: 229 mm
  • No of Pages: 28
  • Spine Width: 2 mm
  • Width: 152 mm
  • ISBN-10: 8618850446
  • Publisher Date: 27 Feb 2020
  • Binding: Paperback
  • Language: English
  • Returnable: N
  • Weight: 68 gr


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