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Conception, développement et caractérisation in vitro de comprimés de dofétilide

Conception, développement et caractérisation in vitro de comprimés de dofétilide

          
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About the Book

L'objectif de ce livre est de développer et de caractériser un système d'administration pulsatile d'un nouveau médicament, le dofétilide. Initialement, les comprimés de base ont été préparés en utilisant différentes concentrations de super désintégrants, les comprimés de base formulés ont été enrobés avec les polymères en utilisant la technologie d'enrobage par compression. Le glycollate d'amidon sodique, la povidone croisée et la carmellose sodique croisée étaient les super désintégrants utilisés dans la formulation des comprimés de base. Toutes les formulations de comprimés enrobés par pressage ont été soumises à divers tests d'évaluation physique et chimique pour les comprimés enrobés par pressage et les comprimés enrobés par pressage. L'épaisseur, la dureté et la variation de poids de toutes les formulations de comprimés se sont révélées conformes aux limites officielles de la pharmacopée. L'enrobage par compression a été réalisé en utilisant Eudragit S 100, Eudragit L 100 et l'éthylcellulose comme polymères d'enrobage. Les données relatives à la libération maximale du médicament ont été obtenues en utilisant une combinaison de polymères dans un rapport de 1:1. Ce livre sera certainement utile aux chercheurs qui souhaitent concevoir et fabriquer des systèmes d'administration de médicaments pulsatiles pour de meilleurs résultats thérapeutiques.


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Product Details
  • ISBN-13: 9786208035679
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Editions Notre Savoir
  • Height: 229 mm
  • No of Pages: 68
  • Spine Width: 4 mm
  • Width: 152 mm
  • ISBN-10: 6208035678
  • Publisher Date: 31 Aug 2024
  • Binding: Paperback
  • Language: French
  • Returnable: N
  • Weight: 114 gr


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Conception, développement et caractérisation in vitro de comprimés de dofétilide
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