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Combinare biologia e chimica per colpire il virus dell'influenza

Combinare biologia e chimica per colpire il virus dell'influenza

          
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About the Book

Questo libro presenta una raccolta di articoli dal 2009 al 2017 sulla caratterizzazione delle proteine del virus dell'influenza A come bersagli farmacologici. Esemplifica la strategia di combinare informazioni biologiche e chimiche evolutive per prevedere i siti bersaglio dei farmaci sulle proteine del virus dell'influenza che difficilmente porteranno alla resistenza ai farmaci. Inoltre, viene applicato uno screening virtuale computazionale per prevedere potenziali inibitori della replicazione della proteina di base della polimerasi 2. Il lettore viene informato sulle strategie per dedurre la conservazione della sequenza delle proteine da sequenze altamente ridondanti e su come combinare la conservazione della sequenza con la previsione dei siti di legame dei farmaci. Questo libro è una risorsa utile per i ricercatori del mondo accademico e dell'industria che iniziano progetti di scoperta di farmaci contro agenti patogeni con un'elevata variabilità di sequenza, come i virus a RNA.


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Product Details
  • ISBN-13: 9786208101220
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Edizioni Sapienza
  • Height: 229 mm
  • No of Pages: 100
  • Spine Width: 6 mm
  • Width: 152 mm
  • ISBN-10: 6208101220
  • Publisher Date: 19 Sep 2024
  • Binding: Paperback
  • Language: Italian
  • Returnable: N
  • Weight: 159 gr


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