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Bewertung der Toxizität von Cypermethrin in Labormäusen

Bewertung der Toxizität von Cypermethrin in Labormäusen

          
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About the Book

Cypermethrin, ein synthetisches Pyrethroid-Insektizid mit einem schnell wirkenden Neurotoxin, von dem bekannt ist, dass es durch freie Radikale vermittelte Gewebeschäden bei einer Vielzahl von Tieren verursacht, wurde hier bei Labor-Albinomäusen (Mus musculus L.) verwendet, um seine Toxizität im Hinblick auf Verhalten und klinische Anzeichen zu bewerten, begleitet von morphometrischen, histopathologischen und hämatologischen Veränderungen bei den Versuchstieren. Männliche Mäuse ( 20g) erhielten jede Woche in vier aufeinanderfolgenden Wochen 0,10mL-0,25mL-1 Körpergewicht Cypermethrin intraperitoneal. Schwere histopathologische Veränderungen, insbesondere in der Leber und den Nieren, verbunden mit Gewichtsverlust der Organe und Nekrosen verschiedener Körperteile, waren zu beobachten. Das hämatologische Profil der mit Cypermethrin behandelten Mäuse zeigte eine statistisch signifikante Abnahme der Erythrozyten, Thrombozyten, des Hämoglobins, der Neutrophilen und Basophilen, aber eine Zunahme der WBK wie Lymphozyten, Monozyten und Eosinophilen. Die Ergebnisse deuten darauf hin, dass Cypermethrin für Säugetiere, einschließlich Menschen, schädlich ist. Daher sollte bei der Anwendung dieses Insektizids auf landwirtschaftlichen Feldern und in Innenräumen darauf geachtet werden, dass es mit Bedacht eingesetzt wird.


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Product Details
  • ISBN-13: 9786206987215
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Verlag Unser Wissen
  • Height: 229 mm
  • No of Pages: 128
  • Spine Width: 8 mm
  • Width: 152 mm
  • ISBN-10: 6206987213
  • Publisher Date: 26 Dec 2023
  • Binding: Paperback
  • Language: German
  • Returnable: N
  • Weight: 200 gr


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