Includes the author's work with NASA HQ as a spacecraft designer to increase astronaut safety by using prognostic and health management (PHM) technologies to create a preventive paradigm to replace their current reactive paradigm in which 17 astronauts have died and NASA's largest spacecraft program ever funded terminated as a result. In 2013, the author submitted his research he completed for the Canadian Space Agency's Manned Space program's Predictive Medicine Program to NASA HQ that identified why and how astronauts are damaged permentally from their journey in space with Captain Lisa Nowak's 3 mental illnesses she acquired and was diagnosed with in 2007 after her several 6 month space missions to the International Space Station identified as the proverbial "canary in the coal mine". In response to the author's research, in 2014, NASA began a series of research projects that would refute the claims of the author's research, but surprisingly, affirmed the author's research and found new dangers and new unknown permanent damage that astronauts suffer from going to space. The author compiled the research completed by the agencies and academic institutions NASA funded and edited them to better reflect their results using terms and conclusions that NASA does not want Congress and the general public to learn. The research identifies that working in space is far more dangerous and harmful to anyone expecting to return as healthy as they they left as NASA and the manned space flight industry portrays to the general public to maintain a pro-space exploration support and continue to receive the $18B/year budget that NASA receives from Congress to meet the direction the the President of the United States. Each volume includes specific dangers and specific temporary and permanent damage that occurs from each thus illustrating that the space exploration operations model used by NASA requires replacement with one that includes providing astronauts artificial gravity via rotating space station to replace the existing and antiquated 3-axis stabilized ISS that forces the on-board astronauts to live in micro-gravity and thus suffer unimaginable damage as identified in the results of the research included and the irreparable damage to an astronaut's brain and body that usually shows up long after leaving the astronaut program. The author included as Appendix 1 the outdated 2004 Review of the NASA Astronaut Longitudinal Health Study by the Institute of Medicine that includes the numbers of mental and physical disorders experienced by the astronauts to 2003.