About the Book
The most trusted and up-to-date pharmacology text in medicine -- completely redesigned to make the learning process even more interesting and efficient
5 Star Doody's Review!
"This is the most widely used textbook for teaching pharmacology to health professionals. This 11th edition is far superior to any previous editions....The authors' goals are to provide a complete, authoritative, current, and readable textbook of pharmacology for students in health sciences. Testimony to their success is the widespread use of this work as required textbook for pharmacology courses around the world. This book is used extensively by thousands of medical, pharmacy, podiatry, nursing, and other health professions students to study pharmacology. Likewise, it remains a valuable resource for residents and practicing physicians....I continue to use this book as a required resource for all courses that I teach to medical, nursing, and allied health students. It is authoritative, readable, and supported by numerous learning tools."--Doody's Review Service
Organized to reflect the syllabi in Pharmacology courses, Basic & Clinical Pharmacology covers all the important concepts students need to know about the science of pharmacology and its application to clinical practice. It is acknowledged worldwide as the field?s most current, authoritative, and comprehensive textbook. To be as clinically relevant as possible, the book features a strong focus on the choice and use of drugs in patients and the monitoring of their effects.
Coverage that spans every important aspect of medical pharmacology:
• Basic Principles
• Autonomic Drugs
• Cardiovascular-Renal Drugs
• Drugs with Important Actions on Smooth Muscle
• Drugs that Act in the Central Nervous System
• Drugs Used to Treat Diseases of the Blood, Inflammation, and Gout
• Endocrine Drugs
• Chemotherapeutic Drugs
• Toxicology
NEW to this edition:
• Full-color presentation, including 300+ illustrations
• Case studies introduce clinical problems in many chapters
• Drug summary tables for key information in comparative context
• Descriptions of important newly released drugs, including new immunopharmacologic agents
• Expanded coverage of general concepts relating to newly discovered receptors, receptor mechanisms, and drug transporters
Table of Contents:
Section I. Basic Principles
1. Introduction, Bertram G. Katzung
2. Drug Receptors & Pharmacodynamics, Mark von Zastrow and Henry R. Bourne
3. Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Time Course of Drug Action, Nicholas H.G. Holford
4. Drug Biotransformation, Maria Almira Correia
5. Development and Regulation of Drugs, Barry A. Berkowitz
Section II. Autonomic Drugs
6. Introduction to Autonomic Pharmacology, Bertram G. Katzung
7. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs, Achilles J. Pappano
8. Cholinoceptor-Blocking Drugs, Achilles J. Pappano
9. Adrenoceptor Agonists & Sympathomimetic Drugs, Italo Biaggioni and David Robertson
10. Adrenoceptor Antagonist Drugs, David Robertson and Italo Biaggioni
Section III. Cardiovascular-Renal Drugs 11. Antihypertensive Agents, Neal L. Benowitz
12. Vasodilators & the Treatment of Angina Pectoris, Bertram G. Katzung and Kanu Chatterjee
13. Drugs Used in Heart Failure, Bertram Katzung and William W. Parmley
14. Agents Used in Cardiac Arrhythmias, Joseph R. Hume and Augustus O. Grant
15. Diuretic Agents, Harlan E. Ives
Section IV. Drugs With Important Actions on Smooth Muscle
16. Histamine, Serotonin, & the Ergot Alkaloids, Bertram G. Katzung
17. Vasoactive Peptides, Ian A. Reid
18. The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds, Emer M. Smyth and Garret A. FitzGerald
19. Nitric Oxide, Samie R. Jaffrey
20. Drugs Used in Asthma, Homer A. Boushey
Section V. Drugs That Act In The Central Nervous System
21. Introduction to the Pharmacology of CNS Drugs, Roger A. Nicoll
22. Sedative-Hypnotic Drugs, Anthony J. Trevor and Walter L. Way
23. The Alcohols, Susan B. Masters
24. Antiseizure Drugs, Roger J. Porter and Brian S. Meldrum
25. General Anesthetics, Paul F. White and Anthony J. Trevor
26. Local Anesthetics, Bertram G. Katzung and Paul F. White
27. Skeletal Muscle Relaxants, Paul F. White and Bertram G. Katzung
28. Pharmacologic Management of Parkinsonism & Other Movement Disorders, Michael J. Aminoff
29. Antipsychotic Agents & Lithium, Herbert Meltzer
30. Antidepressant Agents, Charles DeBattista
31. Opioid Analgesics & Antagonists, Mark A. Schumacher, Allan I. Basbaum, and Walter L. Way
32. Drugs of Abuse, Christian Luscher
Section VI. Drugs Used to Treat Diseases of the Blood, Inflammation, & Gout
33. Agents Used in Anemias; Hematopoietic Growth Factors, Susan B. Masters
34. Drugs Used in Disorders of Coagulation, James L. Zehnder
35. Agents Used in Dyslipidemia, Mary J. Malloy and John P. Kane
36. Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, and Drugs Used in Gout, Daniel E. Furst, Robert W. Ulrich, and Cissy Varkey-Altamirano
Section VII. Endocrine Drugs
37. Hypothalamic & Pituitary Hormones, Susan B. Masters
38. Thyroid & Antithyroid Drugs, Betty J. Dong and Francis S. Greenspan
39. Adrenocorticosteroids & Adrenocortical Antagonists, George P. Chrousos
40. The Gonadal Hormones & Inhibitors, George P. Chrousos
41. Pancreatic Hormones & Antidiabetic Druigs, Martha S. Nolte
42. Agents That Affect Bone Mineral Homeostasis, Daniel D. Bikle
Section VIII. Chemotherapeutic Drugs
43. Beta-Lactam & Other Cell Wall- & Membrane Active Antibiotics, Henry F. Chambers and Daniel H. Deck
44. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidinones, Henry F. Chambers and Daniel H. Deck
45. Aminoglycosides & Spectinomycin, Henry F. Chambers and Daniel H. Deck
46. Sulfonamides, Trimethoprim, & Quinolones, Henry F. Chambers and Daniel H. Deck
47. Antimycobacterial Drugs, Henry F. Chambers and Daniel H. Deck
48. Antifungal Agents, Don Sheppard and Harry W. Lampiris
49. Antiviral Agents, Sharon Safrin
50. Miscellaneous Antimicrobial Agents; Disinfectants, Antiseptics, & Sterilants, Henry F. Chambers and Daniel H. Deck
51. Clinical Use of Antimicrobial Agents, Harry W. Lampiris and Daniel S. Maddix
52. Antiprotozoal Drugs, Philip J. Rosenthal
53. Clinical Pharmacology of the Antihelminthic Drugs, Philip J. Rosenthal
54. Cancer Chemotherapy, Edward Chu and Alan C. Sartorelli
55. Immunopharmacology, Douglas F. Lake, Adrienne D. Briggs, and Emmanuel T. Akporiaye
Section IX. Toxicology
56. Introduction to Toxicology: Occupational & Environmental, Daniel T. Teitelbaum
57. Heavy Metal Intoxication & Chelators, Michael J. Kosnett 58. Management of the Poisoned Patient, Kent R. Olson
Section X. Special Topics
59. Special Aspects of Perinatal & Pediatric Pharmacology, Gideon Koren
60. Special Aspects of Geriatric Pharmacology, Bertram G. Katzung
61. Dermatologic Pharmacology, Dirk B. Robertson and Howard I. Maibach
62. Drugs Used in the Treatment of Gastrointestinal Diseases, Kenneth R. McQuaid
63. Therapeutic & Toxic Potential of Over-the-Counter Agents, Robin L. Corelli
64. Dietary Supplements & Herbal Medications, Cathi E. Dennehy and Candy Tsourounis
65. Rational Prescribing & Prescription Writing, Paul W. Lofholm and Bertram G. Katzung
66. Important Drug Interactions & Their Mechanisms, John R. Horn
Appendix: Vaccines, Immune Globulins, & Other Complex Biologic Products, Harry W. Palpiris and Daniel S. Maddix
Index