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Avaliação de extractos de Euclea crispa leaf contra agentes patogénicos da diarreia

Avaliação de extractos de Euclea crispa leaf contra agentes patogénicos da diarreia

          
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About the Book

A diarreia é uma doença infantil comum com elevada taxa de mortalidade. É o segundo maior assassino de crianças, quase um quinto das crianças com menos de 5 anos morrem devido a desidratação ou imunidade comprometida devido a infecção diarréica. Este estudo visava assim avaliar o efeito do extracto de Euclea crispa leaf e das suas fracções contra a diarreia, causando isolados e determinando a dinâmica da morte por tempo através das fracções potentes. A susceptibilidade dos isolados foi determinada através da difusão do poço de ágar, enquanto as concentrações mínimas bacteriostáticas e bactericidas foram determinadas através do método de diluição do ágar. A dinâmica tempo-morte foi avaliada durante um período de 120 min contra E. coli (1323) representando isolados Gram-negativos. O MIC mais baixo (0,08 mg/ml) é exibido pelas fracções particionadas em acetato de etilo, n-butanol e água, enquanto que essa partição em n-hexano e clorofórmio é de 0,16 mg/ml. A mortalidade total foi alcançada pela fracção de acetato de etilo a uma concentração de 2 × MIC após 120 min de tempo de contacto. Este estudo mostra um potencial antidiarreico significativo de extractos de Euclea crispa leaf e indica igualmente uma fonte de agente terapêutico prontamente disponível contra a infecção diarreica.


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Product Details
  • ISBN-13: 9786205622346
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Edicoes Nosso Conhecimento
  • Height: 229 mm
  • No of Pages: 52
  • Spine Width: 3 mm
  • Width: 152 mm
  • ISBN-10: 6205622343
  • Publisher Date: 25 Jan 2023
  • Binding: Paperback
  • Language: Portuguese
  • Returnable: N
  • Weight: 91 gr


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