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Associação dos Vírus JC e BK e do Regulador da Quinase Dependente de Ciclina

Associação dos Vírus JC e BK e do Regulador da Quinase Dependente de Ciclina

          
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About the Book

O presente estudo foi concebido como um estudo transversal. Foram incluídos 94 fragmentos de carcinoma de células renais fixados em formalina e incluídos em parafina (55 homens e 39 mulheres, com idades compreendidas entre os 18 e os 80 anos). Os dados foram recolhidos a partir de registos de laboratórios histopatológicos do Hospital Universitário Al-Sadder e de alguns laboratórios histopatológicos privados na província de Najaf durante o período de dezembro de 2018 a maio de 2019, utilizando a técnica molecular (reação em cadeia da polimerase) para a deteção de ADN para BKPyV e JCPyV, e a técnica de imuno-histoquímica (IHC) para detetar a expressão de proteínas de marcadores de reguladores da quinase dependentes da ciclina (KAP ou CDKN3 e ciclina E1).Inicialmente, estes casos são examinados histopatologicamente através da coloração de hematoxilina e eosina (H&E), que foi efectuada por um histopatologista consultor para garantir a existência de carcinoma das células renais. Os resultados actuais da técnica de imunohistoquímica (IHC) mostraram que existia uma percentagem positiva mais elevada do marcador KAP ou CDKN3 65 (69,15% em 94 tecidos), enquanto existia uma percentagem positiva mais baixa do marcador Cyclin E1 13 (13,83% em 94 tecidos).


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Product Details
  • ISBN-13: 9786206675358
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Edicoes Nosso Conhecimento
  • Height: 229 mm
  • No of Pages: 192
  • Spine Width: 11 mm
  • Width: 152 mm
  • ISBN-10: 6206675351
  • Publisher Date: 15 Nov 2023
  • Binding: Paperback
  • Language: Portuguese
  • Returnable: N
  • Weight: 291 gr


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