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Association entre le SNP du gène de l'interleukine 35 et le LED en Egypte

Association entre le SNP du gène de l'interleukine 35 et le LED en Egypte

          
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About the Book

Contexte: Le lupus érythémateux systémique (LED) est une maladie du tissu conjonctif auto-immune caractérisée par une tolérance immunitaire réduite du système immunitaire de l'organisme et une énorme production d'auto-anticorps, qui finissent par causer des dommages à la plupart des tissus et organes de l'organisme, y compris la peau, le sang et son diagnostic précoce est important pour réduire les complications.Objectif du travail: Cette étude visait à étudier la possibilité d'un lien entre un polymorphisme mononucléotidique (SNP) dans le gène IL-35 (rs4740) et la susceptibilité à l'apparition du LED.Sujets et méthodologie: Dans cette étude observationnelle, 30 patients déjà diagnostiqués avec un LED (groupe 1) ont été comparés à 20 sujets apparemment sains (groupe 2) appariés en termes d'âge et de sexe (tous des femmes) et n'ayant aucun antécédent de maladie auto-immune. Suite au consentement éclairé pour la recherche scientifique du Comité d'éthique d'Al-Azhar pour la recherche scientifique, des patients et un groupe témoin ont été inscrits dans cette étude. Résultats: Les résultats ont révélé qu'il n'y avait pas de différence d'âge statistiquement significative entre les patients atteints de LED et les témoins sains dans cette étude.


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Product Details
  • ISBN-13: 9786207226603
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Editions Notre Savoir
  • Height: 229 mm
  • No of Pages: 120
  • Spine Width: 7 mm
  • Width: 152 mm
  • ISBN-10: 6207226607
  • Publisher Date: 29 Feb 2024
  • Binding: Paperback
  • Language: French
  • Returnable: N
  • Weight: 186 gr


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Association entre le SNP du gène de l'interleukine 35 et le LED en Egypte
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