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Apoptose na parede da veia nativa utilizada para acesso à hemodiálise

Apoptose na parede da veia nativa utilizada para acesso à hemodiálise

          
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About the Book

Em consonância com o crescente interesse pelo estudo da apoptose em vasos sanguíneos, este estudo é um dos primeiros a avaliar a apoptose em veias nativas utilizadas para fístulas arteriovenosas (FAV) realizadas para hemodiálise. O objetivo deste estudo foi avaliar a apoptose em veias nativas previamente puncionadas (grupo de estudo) em comparação com veias nativas não puncionadas (controles) em pacientes submetidos a procedimento cirúrgico para FVA como acesso para diálise. Foram obtidas amostras de veias cefálicas de 60 pacientes antes da colocação da FAV. Metade dos espécimes eram de veias previamente puncionadas e a outra metade de veias não puncionadas. Um segmento de 1 cm de comprimento foi excisado da parte distal da veia cefálica, dividido em duas porções ao longo do eixo longitudinal e preparado para análise imunohistoquímica. A avaliação imunohistoquímica e a quantificação dos sinais foram utilizadas para avaliar a expressão de Bax, p53, caspase 3 e Bcl-2. A associação que encontrámos entre veias previamente puncionadas e apoptose indica o papel que a punção venosa pode ter no desenvolvimento da apoptose. Os doentes com apoptose aumentada apresentaram um aumento da falência da fístula.


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Product Details
  • ISBN-13: 9786207964048
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Edicoes Nosso Conhecimento
  • Height: 229 mm
  • No of Pages: 64
  • Spine Width: 4 mm
  • Width: 152 mm
  • ISBN-10: 6207964047
  • Publisher Date: 19 Aug 2024
  • Binding: Paperback
  • Language: Portuguese
  • Returnable: N
  • Weight: 109 gr


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Apoptose na parede da veia nativa utilizada para acesso à hemodiálise
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