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Apoptose in nativen Venenwänden, die für Hämodialysezugänge verwendet werden

Apoptose in nativen Venenwänden, die für Hämodialysezugänge verwendet werden

          
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About the Book

Im Einklang mit dem wachsenden Interesse an der Untersuchung der Apoptose in Blutgefäßen ist diese Studie eine der ersten, die die Apoptose in nativen Venen untersucht, die für arteriovenöse Fisteln (AVF) für die Hämodialyse verwendet werden. Ziel dieser Studie war die Bewertung der Apoptose in zuvor punktierten nativen Venen (Studiengruppe) im Vergleich zu nicht punktierten nativen Venen (Kontrollen) bei Patienten, die sich einem chirurgischen Eingriff für eine AVF als Dialysezugang unterziehen. Von 60 Patienten wurden vor der Anlage einer AVF Proben aus der Kopfvene entnommen. Die Hälfte der Proben stammte aus den zuvor punktierten und die andere Hälfte aus den nicht punktierten Venen. Ein 1 cm langes Segment wurde aus dem distalen Teil der Vena cephalica entnommen, entlang der Längsachse in zwei Teile geteilt und für die immunhistochemische Analyse vorbereitet. Die immunhistochemische Bewertung und Quantifizierung der Signale diente zur Beurteilung der Expression von Bax, p53, Caspase 3 und Bcl-2. Der von uns gefundene Zusammenhang zwischen zuvor punktierten Venen und Apoptose weist auf die Rolle hin, die die Venenpunktion bei der Entwicklung der Apoptose spielen kann. Patienten mit erhöhter Apoptose zeigten ein erhöhtes Fistelversagen.


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Product Details
  • ISBN-13: 9786207964000
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Verlag Unser Wissen
  • Height: 229 mm
  • No of Pages: 64
  • Spine Width: 4 mm
  • Width: 152 mm
  • ISBN-10: 6207964004
  • Publisher Date: 19 Aug 2024
  • Binding: Paperback
  • Language: German
  • Returnable: N
  • Weight: 109 gr


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Apoptose in nativen Venenwänden, die für Hämodialysezugänge verwendet werden
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