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Agentes anti-diabéticos não insulínicos e resultados cardiovasculares

Agentes anti-diabéticos não insulínicos e resultados cardiovasculares

          
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International Edition


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About the Book

A diabetes tipo 2 é um importante fator de risco para a insuficiência cardíaca. O tratamento com agentes anti-diabéticos não insulínicos em doentes diabéticos de tipo 2 com doenças cardiovasculares é complexo. A A1C nem sempre reflecte o estado real do controlo da glicose nos doentes diabéticos. Recomenda-se que os algoritmos de tratamento mais recentes sejam adaptados a todos os doentes diabéticos de tipo 2, de acordo com a ADA e a EASD, a fim de atrasar ou prevenir as complicações agudas e crónicas da diabetes. A metformina continua a ser segura no que respeita à redução dos resultados cardiovasculares como o enfarte do miocárdio e as doenças coronárias na diabetes de tipo 2. Várias classes de medicamentos para a diabetes são questionáveis em termos de segurança para a insuficiência cardíaca, como os TZD, possivelmente alguns DPP-4-i e SU. No nosso estudo original com doentes diabéticos de tipo 2, para além do efeito benéfico na resistência à insulina, a glimepirida não demonstrou melhoria na disfunção diastólica, mas não foi evidente um agravamento desta função. Os SGLT2-i e GLP-1RA, para além do controlo da glicemia, parecem ser seguros, com mecanismos de ação específicos, na prevenção da insuficiência cardíaca e na redução da morte cardiovascular na diabetes tipo 2.


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Product Details
  • ISBN-13: 9786207780693
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Edicoes Nosso Conhecimento
  • Height: 229 mm
  • No of Pages: 52
  • Spine Width: 3 mm
  • Width: 152 mm
  • ISBN-10: 6207780698
  • Publisher Date: 12 Jul 2024
  • Binding: Paperback
  • Language: Portuguese
  • Returnable: N
  • Weight: 91 gr


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