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Adult Patients Pre and Post- Liver Transplant Nutritional Profile

Adult Patients Pre and Post- Liver Transplant Nutritional Profile

          
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About the Book

Liver Transplantation (LT) is the only treatment for patients with End Stage Liver disease

(ESLD). Malnutrition is widely prevalent in ESLD patients and is associated with poor

surgery outcome. The present study is aimed at assessing pre and post nutritional status of

patients undergoing LT in Delhi. From 3 multispecialty hospitals undertaking LT in Delhi

and NCR, 54 LT recipients were recruited as study sample. The data on general, medical,

dietary history was gathered using quantitative and qualitative methods. Standardized

techniques for assessing disease prognosis, nutrition status, dietary intake, appetite, body

composition, Quality of Life (QoL), Performance Status (PS) were used. The data was

analyzed using SPSS (version-17) and Dietcal software(c) 2014 (Version 5.0).

Majority of the patients were males, Indians, in age range of 46-53 years. 27.8% and 22.2%

of the patients were having Hepatitis C Virus related Chronic Liver Disease and ethanol

related Chronic Liver Disease respectively. 61.1% of the patients were having Child Turcotte

Pugh (CTP) Grade C and 51.9% of the patients with Model for End stage Liver Disease

(MELD) score of 19-24 depicting higher disease severity and urgency of transplantation. The

diet history of the patients showed majority of the patients were having no food allergy,

average appetite, with Simplified Nutritional Appetite Questionnaire score (SNAQ) >14.

68.5% of the patients were having fluid restrictions, 31.5% of the patients were alcoholics

according to CAGE questionnaire. QoL assessment by Short Form-36 questionnaire showed

significantly lower scores in LT recipients than the age and sex matched control group. The

QoL scores did not show any significant association with CTP and MELD scores. The PS

assessment showed 51.2% of the patients were ambulatory and capable of all self-care but

unable to carry out any work activities and 14% of the patients were completely disabled.

Nutrition status assessment in patients undergoing LT is difficult, because of the symptoms

like ascites and hypo-albuminemia which affects the traditional markers of nutrition. The

nutrition status assessment by various tools like Anthropometry, Biochemical Parameter

(Albumin), Subjective Global Assessment (SGA), Hand Grip Strength (HG) and body

composition analysis by BIA (Phase Angle) showed varied prevalence of malnutrition. 88.9%

of the patients were malnourished according to SGA and albumin, 100% of patients were

malnourished by HG and 75% of the patients were depicted malnourished by phase angle.

The present study showed that SGA has moderate agreement with body's phase angle and

was also associated with various clinical, prognostic, therapeutic and nutritional variables of

LT. Pre-LT malnutrition was significantly related to higher disease severity, tense ascites,

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Product Details
  • ISBN-13: 9787983673889
  • Publisher: Basma Publishing
  • Binding: Paperback
  • Language: English
  • Returnable: Y
  • Weight: 331 gr
  • ISBN-10: 7983673884
  • Publisher Date: 11 Nov 2022
  • Height: 229 mm
  • No of Pages: 244
  • Spine Width: 13 mm
  • Width: 152 mm


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