Stanton L Gerson

Stanton L GersonStanton L Gerson is Director of the Case Comprehensive Cancer Center & the National Center for Regenerative Medicine at Case Western Reserve University and Director of University Hospitals Seidman Cancer Center in Cleveland. Dr. Gerson studies DNA reair, stem cells and cancer therapy. He showed that over-expression of the MGMT DNA repair gene could prevent cancer and that a mutant form of MGMT protects hematopoietic stem cells from chemotherapy using lentiviral gene therapy. He has interrogated MGMT, MMR and BER DNA repair pathways as targets for cancer therapy, and proposed that methoxyamine would block base excision repair used in combination with chemotherapy. Dr. Gerson also directed the initial use of mesenchymal stem cells (MSCs) in bone marrow transplantation & in gene therapy. Read More Read Less

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Gene Therapy of Cancer48 %
Publisher: Academic Press Inc
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01 Jan 1999
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Clinical Hematology [With CDROM]43 %
Publisher: Mosby
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20/12/20
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Gene Therapy of Cancer: Translational Approaches from Preclinical Studies to Clinical Implementation
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