Rajshekhar KarpoormathRajshekhar Karpoormath's research group at University of KwaZulu-Natal, South Africa specialises on the synthesis of aza-heterocycles and their pharmacological applications. One such versatile scaffold of our research interest is pyrazolopyrimidines nd their broad range of medicinal applications. We have published several review articles on aza-heterocycles and recently published two full review articles in European Journal of Medicinal Chemistry (2017) 126, 298-352 and Bioorganic & Medicinal Chemistry (2018), 26(2), 309-339 on pyrazolo[1,5-a]pyrimidine and pyrazolo[4,3-d]pyrimidine scaffolds respectively. Our exercise of writing the two reviews on pyrazolopyrimidine analogues has given us good understanding and knowledge on this scaffold. In addition we have studied and collected extensive literature on this topic, thus having required credentials and knowledge in writing an extensive book on pyrazolopyrimidine with special emphasis on their medicinal applications and Structure Activity Relationship (SAR) Studies. Read More Read Less