Mariah LelosMy PhD (2005-2010, Prof M Good) investigated neural network dysfunction using mathematical modelling in a mouse model of Alzheimer's disease, with a particular focus on amyloid-induced dysfunction in the amydala and hippocampal formation. My post-docoral research (2010-2015, Prof S Dunnett) aimed to understand basal ganglia dysfunction in Parkinson's and Huntington's disease and to explore the use of human fetal and novel stem cell derived therapies to alleviate the behavioural impairments. I was awarded a Senior Research Fellowship from Parkinson's UK (2015-2018) to investigate the ability of human stem cell derived cell therapy products to ameliorate cognitive impairments in rodent models of Parkinson's disease. I have recently commenced a Senior Lectureship in the neuroscience department and my lab is exploring several new avenues. We are seeking to establish novel cell therapies to treat Parkinson's and Huntington's diseases, using novel DREADDs manipulations, undertaking PET/MR imaging and using rabies tracing technologies. We are also studying the impact of novel gene therapies on cellular function and on cognitive dysfunction. Read More Read Less