John G NuttI have two main research areas. The first theme is the pharmacology of movement disorders. My studies have largely been proof of principle clinical trials of dopaminergic therapies. I have developed protocol using 2-hour levodopa infusions and four smple clinical tests (tapping speed, timed up and go tremor score and dyskinesia score) for investigating pharmacodynamics of levodopa and interactions between levodopa and other interventions. The second theme is gait and balance dysfunction with clinical interests in gait disorders and interests in the physiology of gait and balance in neurological disorders. David Marsden, Phillip Thompson and I introduced the concept of lower, middle and higher level gait disorders that is widely accepted today. Dr. Horak, with whom I have collaborated for over 30 years, and I have investigated the physiology of balance and gait disorders that characterizes Parkinson's disease. Read More Read Less