James R SowersJames R. Sowers, MD, is Professor of Medicine, Physiology/Pharmacology and Director of the Endocrinology, Diabetes & Metabolism Division at the University Of Missouri, School Of Medicine. In addition, he is the Director of the Thomas and Joan Burns Crdiovascular and Diabetes Research Center and holds the Thomas W. and Joan F. Burns Missouri Chair in Diabetology. Dr. Sowers serves as a reviewer on several study sections for the National Institutes of Health and for the Department of Veterans Affairs. He is the editor of Cardiorenal Medicine, Associate Editor of Diabetes and on editorial boards of Hypertension, Endocrinology, and Metabolism. In the last year Dr. Sowers has published more than 25 peer-reviewed papers.
Dr. Sowers achieved the Irvin Page Lifetime Achievement Award from the American Heart Association in 2012. He serves as a PI on one NIH funded grant and a VA Merit grant, and is a Co-Investigator on several NIH grants with colleagues at the University of Missouri, as well as other research colleagues at academic institutions around the country.
Dr. Sowers has been examining the cellular mechanisms of insulin action in cardiovascular, renal and skeletal muscle tissue for three decades, focusing primarily on in vitro and in vivo/ex-vivo studies of animal models. Recently his research has been directed to the role of over-nutrition/angiotensin II, aldosterone, estrogen, and immune function on T regulatory cells and in site-specific serine phosphorylation of insulin sensitivity and associated cardiovascular functional abnormalities. As part this continuing cardiovascular renal diabetes research program, his program plans to pursue the role of angiotensin II, aldosterone and sex differences in metabolic cardiovascular insulin resistance in mice subjected to a "Westernized" diet. Read More Read Less